Evidence map›Paper›PMID 28066373›Full record

ArticleFrontiers in microbiology2016

Cinnamaldehyde Inhibits

Thiago A F Ferro, Jéssica M M Araújo, Bruna L Dos Santos Pinto, Jéssica S Dos Santos, Eliene B Souza, Bruna L R da Silva, Valderlane L P Colares, Tânia M G Novais, Clovis M B Filho, Carsten Struve and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Effect ofPathogens (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
  5. Cinnamaldehyde effectively disruptsApplied and environmental microbiology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Immunomodulatory Effects of Cinnamaldehyde inMolecules (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Antibiofilm Activities of Cinnamaldehyde Analogs against UropathogenicInternational journal of molecular sciences · 2022
    Article
  15. Colonization and Infection of Indwelling Medical Devices byInternational journal of molecular sciences · 2022
    Review
  16. Antibacterial Fractions fromAntibiotics (Basel, Switzerland) · 2022
    Article
  17. Loratadine inhibitsiScience · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Thiago A F FerroPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Jéssica M M AraújoPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Bruna L Dos Santos PintoPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Jéssica S Dos SantosPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Eliene B SouzaPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Bruna L R da SilvaPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Valderlane L P ColaresPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Tânia M G NovaisPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Clovis M B FilhoUniversidade Federal de Pernambuco Pernambuco, Brazil.
Carsten StruveStatens Serum Institut Copenhagen, Denmark.
João B CalixtoCentro de Inovação e Estudos Pré-clínicos Florianópolis, Brazil.
Valério Monteiro-NetoPrograma de Pós-graduação, Universidade CEUMASão Luís, Brazil; Universidade Federal do MaranhãoSão Luís, Brazil.
Luís C N da SilvaPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Elizabeth S FernandesPrograma de Pós-graduação, Universidade CEUMA São Luís, Brazil.
Centro Universitário do Maranhão · BRUniversidade Luterana do Brasil · BRCentro de Pesquisas Oncológicas · BRStatens Serum Institut · DKUniversidade de Pernambuco · BRUniversidade Federal do Maranhão · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial resistance to the available marketed drugs has prompted the search of novel therapies; especially in regards of anti-virulence strategies that aim to make bacteria less pathogenic and/or decrease their probability to become resistant to therapy. Cinnamaldehyde is widely known for its antibacterial properties through mechanisms that include the interaction of this compound with bacterial cell walls. However, only a handful of studies have addressed its effects on bacterial virulence, especially when tested at sub-inhibitory concentrations. Herein, we show for the first time that cinnamaldehyde is bactericidal against

Indexed as

bacterial virulencecinnamaldehydeessential oilinfectionS. aureus

Identifiers

PMID28066373
PMCPMC5174152
OpenAlexW2565257736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.