ArticleFrontiers in neurology2016
Spatiotemporal Mapping of Interictal Spike Propagation: A Novel Methodology Applied to Pediatric Intracranial EEG Recordings.
Article in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Mapping intraoperative interictal epileptiform discharges using high-resolution, thin-film cortical arrays.Epilepsia · 2026Article
- Ictal MEG-EEG Study to Localize the Onset of Generalized Seizures: To See Beyond What Meets the Eye.Brain sciences · 2025Article
- Interictal spikes and evoked cortical potentials share common spatiotemporal constraints in human epilepsy.Frontiers in network physiology · 2025Article
- Co-activation of interictal epileptiform discharges localizes seizure onset zone and fluctuates with brain state.Brain communications · 2025Article
- Overlap of spike and ripple propagation onset predicts surgical outcome in epilepsy.Annals of clinical and translational neurology · 2024Article
- Visualization of the Spatiotemporal Propagation of Interictal Spikes in Temporal Lobe Epilepsy: A MEG Pilot Study.Brain topography · 2024Article
- Identifying sources of human interictal discharges with travelling wave and white matter propagation.Brain : a journal of neurology · 2023Article
- Spike propagation mapping reveals effective connectivity and predicts surgical outcome in epilepsy.Brain : a journal of neurology · 2023Article
- Interictal discharges in the human brain are travelling waves arising from an epileptogenic source.Brain : a journal of neurology · 2023Article
- The spatial relationship between the MRI lesion and intraoperative electrocorticography in focal epilepsy surgery.Brain communications · 2022Article
- Electric Source Imaging on Intracranial EEG Localizes Spatiotemporal Propagation of Interictal Spikes in Children with Epilepsy.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021Article
- Microscale dynamics of electrophysiological markers of epilepsy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Interictal spike networks predict surgical outcome in patients with drug-resistant focal epilepsy.Annals of clinical and translational neurology · 2021Article
- Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset.Brain : a journal of neurology · 2020Article
- The seizure onset zone drives state-dependent epileptiform activity in susceptible brain regions.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2019Article
- Reproducibility of interictal spike propagation in children with refractory epilepsy.Epilepsia · 2019Article
- Interictal spike connectivity in human epileptic neocortex.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2019Article
- A predictive epilepsy index based on probabilistic classification of interictal spike waveforms.PloS one · 2018Article
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6 authors.
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Abstract
Synchronized cortical activity is implicated in both normative cognitive functioning and many neurologic disorders. For epilepsy patients with intractable seizures, irregular synchronization within the epileptogenic zone (EZ) is believed to provide the network substrate through which seizures initiate and propagate. Mapping the EZ prior to epilepsy surgery is critical for detecting seizure networks in order to achieve postsurgical seizure control. However, automated techniques for characterizing epileptic networks have yet to gain traction in the clinical setting. Recent advances in signal processing and spike detection have made it possible to examine the spatiotemporal propagation of interictal spike discharges across the epileptic cortex. In this study, we present a novel methodology for detecting, extracting, and visualizing spike propagation and demonstrate its potential utility as a biomarker for the EZ. Eighteen presurgical intracranial EEG recordings were obtained from pediatric patients ultimately experiencing favorable (i.e., seizure-free,
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