Evidence map›Paper›PMID 28066142›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2017

Participation of central GABA

Min Ji Kim, Young Hong Park, Kui Ye Yang, Jin Sook Ju, Yong Chul Bae, Seong Kyu Han, Dong Kuk Ahn

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. The P2X7 Hypothesis of Central Post-Stroke Pain.International journal of molecular sciences · 2024
    Article
  2. Review
  3. Article
  4. Preemptive application of QX-314 attenuates trigeminal neuropathic mechanical allodynia in rats.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2018
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Min Ji KimDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Young Hong ParkDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Kui Ye YangDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Jin Sook JuDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Yong Chul BaeDepartment of Oral Anatomy, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Seong Kyu HanDepartment of Oral Physiology, School of Dentistry and Institute of Oral Bioscience, Chonbuk National University, Jeonju 54896, Korea.
Dong Kuk AhnDepartment of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu 41940, Korea.
Jeonbuk National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we investigated the central processing mechanisms of mechanical allodynia and found a direct excitatory link with low-threshold input to nociceptive neurons. Experiments were performed on male Sprague-Dawley rats weighing 230-280 g. Subcutaneous injection of interleukin 1 beta (IL-1β) (1 ng/10 µL) was used to produce mechanical allodynia and thermal hyperalgesia. Intracisternal administration of bicuculline, a gamma aminobutyric acid A (GABA

Indexed as

GABAA receptorIL-1βMechanical allodyniaNKCC1Paradoxical anti-allodynic effect

Identifiers

PMID28066142
PMCPMC5214912
OpenAlexW2569547600

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.