Evidence map›Paper›PMID 28066068›Full record

ArticleTransactions of the American Clinical and Climatological Association2016

LEUKOCYTE LIPID BODIES - STRUCTURE AND FUNCTION AS "EICOSASOMES".

Peter F Weller

Open access · greenAbstract read
In one paragraph

Article in Transactions of the American Clinical and Climatological Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Can Bisphenols Alter the Inflammation Process?Life (Basel, Switzerland) · 2025
    Review
  2. Vascular ATGL-dependent lipolysis and the activation of cPLACellular and molecular life sciences : CMLS · 2024
    Article
  3. iScience · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Macroalgal Proteins: A Review.Foods (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Arachidonic Acid Metabolites in Cardiovascular and Metabolic Diseases.International journal of molecular sciences · 2018
    Review
  15. Synopsis of arachidonic acid metabolism: A review.Journal of advanced research · 2018
    Review
  16. Leptin Elicits LTCFrontiers in immunology · 2018
    Article
  17. Leptin MediatesFrontiers in immunology · 2018
    Article
  18. Adipocytes, mast cells and angiogenesis.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Peter F WellerBOSTON, MASSACHUSETTS.

Funding

CYTOPLASMIC LIPID BODIES OF INFLAMMATORY CELLSR01AI022571 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WELLER, PETER F · 1985 to 2013
$4.5M
Human Eosinophils: Mechanisms of FunctioningR37AI020241 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI WELLER, PETER F · 2010 to 2019
$4.5M
NIAID NIH HHS R01 AI022571NIAID NIH HHS R37 AI020241
6 · The paper itself

Abstract

Lipid bodies are cytoplasmic inclusions that develop within leukocytes, including eosinophils and neutrophils, associated with inflammation. Our investigations of the formation and function of lipid bodies have revealed that they are distinct, inducible endoplasmic reticulum-derived, membrane- and ribosome-containing organelles with diverse functional roles in inflammatory responses of leukocytes. Leukocyte lipid bodies contain all enzymes required for synthesizing cyclo-oxygenase- and lipoxygenase-derived eicosanoids. Lipid body formation, rapidly inducible

Indexed as

AnimalsArachidonic AcidEicosanoidsLeukocytesLipid DropletsSignal TransductionArachidonic AcidEicosanoids

Identifiers

PMID28066068
PMCPMC5216467
OpenAlexW2582268132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.