Evidence map›Paper›PMID 28065772›Full record

ArticleThe American journal of medicine2017

Multimorbidity in Middle-Aged Adults with Cerebral Palsy.

Nicole Cremer, Edward A Hurvitz, Mark D Peterson

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 158 citations in OpenAlex.

  1. Pooled it
  2. A pilot study proposing an algorithm for pubertal induction in cerebral palsy.Journal of pediatric endocrinology & metabolism : JPEM · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nicole CremerUniversity of Michigan, University of Michigan Medical School, Ann Arbor.
Edward A HurvitzDepartment of Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor.
Mark D PetersonDepartment of Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor. Electronic address: mdpeterz@med.umich.edu.
University of Michigan–Ann Arbor · US

Funding

Secondary Muscle Pathology & Metabolic Dysregulation in Adult with Cerebral PalsyK01HD074706 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PETERSON, MARK D · 2013 to 2017
$605k
NICHD NIH HHS K01 HD074706
6 · The paper itself

Abstract

objectiveIndividuals with cerebral palsy have less lean body mass, greater relative adiposity, and lower fitness and physical activity participation, and yet the prevalence of age-related multimorbidity in this population has yet to be established. The study objective was to examine the prevalence of lifestyle-related chronic conditions and multimorbidity in a sample of middle-aged adults with cerebral palsy.

methodsA clinic-based sample of middle-aged adults with cerebral palsy was examined using Electronic Medical Records Search Engine software. Our cohort included 435 individuals aged 40 to 60 years, with an International Classification of Diseases, Clinical Modification, 9th and 10th Revisions Diagnosis Code for cerebral palsy. Prevalence of 12 chronic conditions was evaluated, including existing diagnoses or historical record of osteopenia/osteoporosis, myocardial infarction, stroke, coronary artery disease, impaired glucose tolerance/type 2 diabetes, other cardiovascular conditions, rheumatoid arthritis, osteoarthritis, asthma, emphysema, prehypertension/hypertension, and hyperlipidemia. Multivariate logistic models were used to estimate multimorbidity (ie, ≥2 chronic conditions), adjusting for age, sex, smoking status, obesity, and Gross Motor Function Classification System (GMFCS).

resultsThere were 137 unique multimorbidity combinations. Multimorbidity was significantly more prevalent among obese versus nonobese individuals for both GMFCS I-III (75.8% vs 53.6%) and GMFCS IV-V (79.0% vs 64.2%), but was also significantly higher in nonobese individuals with GMFCS IV-V (64.2%) compared with nonobese individuals with GMFCS I-III (53.6%). Both the obesity status (odds ratio, 2.20; 95% confidence interval, 1.32-2.79) and the GMFCS IV-V category (odds ratio, 1.81; 95% confidence interval, 1.32-3.68) were independently associated with multimorbidity.

conclusionsMiddle-aged adults with cerebral palsy have high estimates of multimorbidity; both obesity and higher GMFCS levels are independently associated with greater risk.

Indexed as

AdultAsthmaBone Diseases, MetabolicCardiovascular DiseasesCerebral PalsyComorbidityCross-Sectional StudiesHumansMiddle AgedObesityOsteoarthritisOsteoporosisPrevalenceSex FactorsCerebral palsyDiabetesHypertensionMultimorbidityObesityOsteoporosis

Identifiers

PMID28065772
PMCPMC5502778
OpenAlexW2568064743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.