Evidence map›Paper›PMID 28065672›Full record

ArticleMicrovascular research2017

Monitoring microvascular perfusion variations with laser speckle contrast imaging using a view-based temporal template method.

Mohammad Zaheer Ansari, Eun-Jeung Kang, Mioara D Manole, Jens P Dreier, Anne Humeau-Heurtier

Open access · greenAbstract read
In one paragraph

Article in Microvascular research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Mohammad Zaheer AnsariDepartment of Physics, Cambridge Institute of Polytechnic, Baheya, Angara, Ranchi 835103, Jharkhand, India. Electronic address: mohamedzaheer1@gmail.com.
Eun-Jeung KangDepartment of Experimental Neurology, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany; Department of Neurology, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany; Center for Stroke Research, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Mioara D ManoleUniversity of Pittsburgh, Safar Center for Resuscitation Research, USA.
Jens P DreierDepartment of Experimental Neurology, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany; Department of Neurology, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany; Center for Stroke Research, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany.
Anne Humeau-HeurtierUniv Angers, LARIS - Laboratoire Angevin de Recherche en Ingénierie des Systèmes, Angers, France.
Charité - Universitätsmedizin Berlin · DELaboratoire Angevin de Recherche en Mathématiques · FRUniversity of Pittsburgh · US

Funding

CYP 450-mediated CBF Dysregulation and Neurotoxicity in Pediatric Cardiac ArrestR01HD075760 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MANOLE, MIOARA D. · 2013 to 2017
$1.5M
NICHD NIH HHS R01 HD075760
6 · The paper itself

Abstract

purposeLaser speckle contrast imaging (LSCI) continues to gain an increased interest in clinical and research studies to monitor microvascular perfusion. Due to its high spatial and temporal resolutions, LSCI may lead to a large amount of data. The analysis of such data, as well as the determination of the regions where the perfusion varies, can become a lengthy and tedious task. We propose here to analyze if a view-based temporal template method, the motion history image (MHI) algorithm, may be of use in detecting the perfusion variations locations.

methodsLSCI data recorded during three different kinds of perfusion variations are considered: (i) cerebral blood flow during spreading depolarization (SD) in a mouse; (ii) cerebral blood flow during SD in a rat; (iii) cerebral blood flow during cardiac arrest in a rat. Each of these recordings was processed with MHI.

resultsWe show that, for the three pathophysiological situations, MHI identifies the area in which perfusion evolves with time. The results are more easily obtained compared with a visual inspection of all of the frames constituting the recordings. MHI also has the advantage of relying on a rather simple algorithm.

conclusionsMHI can be tested in clinical and research studies to aid the user in perfusion analyses.

Indexed as

AlgorithmsCerebrovascular CirculationCortical Spreading DepressionMicrocirculationAnimalsBlood Flow VelocityCerebral ArteriesDisease Models, AnimalFeasibility StudiesHeart ArrestImage Interpretation, Computer-AssistedLaser-Doppler FlowmetryMicePerfusion ImagingPredictive Value of TestsRats, Inbred WKYBiomedical signal processingCerebral blood flowMicrocirculationMotion history image

Identifiers

PMID28065672
PMCPMC6353663
OpenAlexW2569029990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.