Evidence map›Paper›PMID 28065451›Full record

ArticleAnnals of epidemiology2017

Home remodeling and risk of childhood leukemia.

Todd P Whitehead, Praphopphat Adhatamsoontra, Yang Wang, Elisa Arcolin, Leonard Sender, Steve Selvin, Catherine Metayer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Todd P WhiteheadSchool of Public Health, University of California, Berkeley. Electronic address: ToddPWhitehead@Berkeley.edu.
Praphopphat AdhatamsoontraSchool of Public Health, University of California, Berkeley.
Yang WangSchool of Public Health, University of California, Berkeley.
Elisa ArcolinDepartment of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Leonard SenderSchool of Medicine, University of California, Irvine.
Steve SelvinSchool of Public Health, University of California, Berkeley.
Catherine MetayerSchool of Public Health, University of California, Berkeley.
University of California, Berkeley · USUniversity of California, Irvine · USUniversity of Modena and Reggio Emilia · IT

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MORELLO-FROSCH, RACHEL ADELE · 1987 to 2025
$74.6M
Environmental and Molecular Epidemiology of Childhood LeukemiaR01ES009137 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI METAYER, CATHERINE · 1999 to 2013
$21.1M
NIEHS NIH HHS P42 ES004705NIEHS NIH HHS R01 ES009137
6 · The paper itself

Abstract

purposeWe investigated the relationship between the risk of childhood leukemia and home remodeling, a surrogate for indoor chemical exposures.

methodsWe collected information on remodeling activities carried out between birth and diagnosis in homes of 609 acute lymphoblastic leukemia (ALL) cases, 89 acute myeloid leukemia (AML) cases, and 893 matched controls participating in the California Childhood Leukemia Study (1995-2008). We used multivariable logistic regression to estimate the risk of ALL and AML associated with six remodeling activities: construction, painting, recarpeting, reflooring, roofing, and weatherproofing. Models were adjusted for age, sex, Hispanic ethnicity, race, household annual income, and residential mobility.

resultsConstruction in the home between birth and diagnosis was associated with a significant increase in ALL risk (odds ratio [OR]: 1.52, 95% confidence interval [CI]: 1.14-2.02) and a nonsignificant increase in AML risk (OR: 1.75, 95% CI: 0.98-3.15). No other remodeling activities were associated with ALL or AML risk in the main analysis. When stratifying by Hispanic ethnicity, a positive relationship between ALL risk and painting was evident in Hispanic children (OR: 1.47, 95% CI: 1.04-2.07).

conclusionsSpecific home remodeling activities appeared to be associated with increased risk of childhood ALL.

Indexed as

AdolescentAir Pollution, IndoorCaliforniaCase-Control StudiesChildChild, PreschoolConstruction MaterialsEnvironmental ExposureEthnicityFemaleHumansInfantLeukemia, Myeloid, AcuteLogistic ModelsMaleOdds RatioChildhood acute lymphoblastic leukemiaChildhood acute myeloid leukemiaConstruction materialsEnvironmental exposures

Identifiers

PMID28065451
PMCPMC5313318
OpenAlexW2560797833

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.