ArticlePsychological medicine2017
The association between childhood adversities and subsequent first onset of psychotic experiences: a cross-national analysis of 23 998 respondents from 17 countries.
Article in Psychological medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 4 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 144 citations in OpenAlex.
- Brain structure and function in adult survivors of developmental trauma with psychosis: A systematic review.Psychological medicine · 2025Pooled it
- Cumulative exposure to childhood adversity and risk of adult psychosis: a dose-response meta-analysis.Psychological medicine · 2025Pooled it
- Traumatic experiences in childhood and adolescence: a meta-analysis of prospective studies assessing risk for psychosis.European child & adolescent psychiatry · 2022Pooled it
- Psychosis in children of separated parents: A systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2020Pooled it
- Neurodevelopmental effects of early life stress: PFC and cognition.Neuroscience and biobehavioral reviews · 2026Review
- Childhood Adversities and Psychosis Across Populations: Insights From the 6-Country EU-GEI Study.Schizophrenia bulletin · 2026Article
- The Association Between Childhood Trauma and Prodromal Psychotic Symptoms in Nursing Undergraduates: Mediating Roles of Depression and Anxiety.Journal of multidisciplinary healthcare · 2026Article
- The victimisation experience schedule: contextualising interpersonal trauma and perceived discrimination in individuals with psychotic experiences with and without a need-for-care.Social psychiatry and psychiatric epidemiology · 2025Article
- Belief Updating, Childhood Maltreatment, and Paranoia in Schizophrenia-Spectrum Disorders.Schizophrenia bulletin · 2025Article
- Golden Snub-Nosed Monkeys: Potential Primate Paradigm in Post-Traumatic Stress Disorder Research.Biology · 2025Article
- Associations between local rates of violence and experiences of psychosis in Trinidad.Frontiers in public health · 2025Article
- Prevalence and associations of adverse childhood experiences with anxiety and depressive symptoms in Indonesia.Frontiers in public health · 2025Article
- Article
- An Explanatory Model to Predict Pediatric Psychosis Spectrum Based on Parent Psychiatric Profile and Children and Adolescents Comorbid Disorders as a Mediator Construct.Iranian journal of psychiatry · 2024Article
- Stress, Environment and Early Psychosis.Current neuropharmacology · 2024Review
- Ruminative thinking mediates the effects of exposure to adverse life events on psychotic-like experiences.Frontiers in psychology · 2024Article
- Suicidal Ideation and Non-Suicidal Self-Injury Following Early Childhood Psychotic Experiences in Preadolescent Children at Familial High Risk of Schizophrenia or Bipolar Disorder-The Danish High Risk and Resilience Study, VIA 11.Schizophrenia bulletin · 2023Article
- Links between trauma and psychosis (Review).Experimental and therapeutic medicine · 2023Review
- [Reliability and validity of the Chinese version of adverse childhood experiences international questionnaire in parents of preschool children].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Early Childhood Neurocognition in Relation to Middle Childhood Psychotic Experiences in Children at Familial High Risk of Schizophrenia or Bipolar Disorder and Population-Based Controls: The Danish High Risk and Resilience Study.Schizophrenia bulletin · 2023Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
30 authors at 20 institutions in 20 countries.
Funding
Abstract
backgroundAlthough there is robust evidence linking childhood adversities (CAs) and an increased risk for psychotic experiences (PEs), little is known about whether these associations vary across the life-course and whether mental disorders that emerge prior to PEs explain these associations.
methodWe assessed CAs, PEs and DSM-IV mental disorders in 23 998 adults in the WHO World Mental Health Surveys. Discrete-time survival analysis was used to investigate the associations between CAs and PEs, and the influence of mental disorders on these associations using multivariate logistic models.
resultsExposure to CAs was common, and those who experienced any CAs had increased odds of later PEs [odds ratio (OR) 2.3, 95% confidence interval (CI) 1.9-2.6]. CAs reflecting maladaptive family functioning (MFF), including abuse, neglect, and parent maladjustment, exhibited the strongest associations with PE onset in all life-course stages. Sexual abuse exhibited a strong association with PE onset during childhood (OR 8.5, 95% CI 3.6-20.2), whereas Other CA types were associated with PE onset in adolescence. Associations of other CAs with PEs disappeared in adolescence after adjustment for prior-onset mental disorders. The population attributable risk proportion (PARP) for PEs associated with all CAs was 31% (24% for MFF).
conclusionsExposure to CAs is associated with PE onset throughout the life-course, although sexual abuse is most strongly associated with childhood-onset PEs. The presence of mental disorders prior to the onset of PEs does not fully explain these associations. The large PARPs suggest that preventing CAs could lead to a meaningful reduction in PEs in the population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.