Evidence map›Paper›PMID 28065176›Full record

ArticleEpidemiology and psychiatric sciences2018

Behavioural and psychological symptoms in general hospital patients with dementia, distress for nursing staff and complications in care: results of the General Hospital Study.

J B Hessler, M Schäufele, I Hendlmeier, M N Junge, S Leonhardt, J Weber, H Bickel

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 61 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 4 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04179721 nacompletednot on this mapstarted 2019, after this paper: background citation

Reducing Behavioral and Psychological Symptoms of Dementia (BPSD) for Acutely-Ill Persons With Alzheimers Disease and Related Dementias Via Patient Engagement Specialists

TypeinterventionalSponsorNorthwell HealthRan2019 to 2021Enrolled54ConditionsAlzheimer's Disease and Related DementiasArmsPES-4-BPSD Model, The attention control condition
NCT04481568 nacompletednot on this mapstarted 2020, after this paper: background citation

Reducing Behavioral and Psychological Symptoms of Dementia (BPSD) for Acutely-Ill Persons With Alzheimers Disease and Related Dementias Via Patient Engagement Specialists

TypeinterventionalSponsorNorthwell HealthRan2020 to 2021Enrolled158ConditionsAlzheimer's Disease and Related DementiasArmsPES-4-BPSD Model, The attention control condition
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 4 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
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  8. Pain Incidence, Treatment, and Associated Symptoms in Hospitalized Persons with Dementia.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Trial
  9. Brexpiprazole for the Treatment of Agitation Associated with Dementia due to Alzheimer's Disease: Clinical Perspectives.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026
    Review
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  18. Carers' experiences and perspectives of the use of anticholinergic medications in people living with dementia: Analysis of an online discussion forum.Health expectations : an international journal of public participation in health care and health policy · 2024
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  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J B HesslerDepartment of Psychiatry and Psychotherapy,Klinikum rechts der Isar,Technical University of Munich,Germany.ORCID 0000-0002-6994-7951
M SchäufeleFaculty of Social Work,Mannheim University of Applied Sciences,Mannheim,Germany.
I HendlmeierFaculty of Social Work,Mannheim University of Applied Sciences,Mannheim,Germany.
M N JungeDepartment of Psychiatry and Psychotherapy,Klinikum rechts der Isar,Technical University of Munich,Germany.
S LeonhardtFaculty of Social Work,Mannheim University of Applied Sciences,Mannheim,Germany.
J WeberFaculty of Social Work,Mannheim University of Applied Sciences,Mannheim,Germany.
H BickelDepartment of Psychiatry and Psychotherapy,Klinikum rechts der Isar,Technical University of Munich,Germany.
Technische Hochschule Mannheim · DETUM Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsLittle is known about how behavioural and psychological symptoms of dementia (BPSD) manifest in the general hospital. The aim was to examine the frequency of BPSD in general hospitals and their associations with nursing staff distress and complications in care.

methodsCross-sectional representative study with 1469 patients aged ≥65, including 270 patients with dementia, of 33 randomly selected general hospitals in Germany. BPSD and complications were reported by nurses.

resultsOverall frequency of BPSD was higher in patients with dementia (76%) than without (38%). The most frequent symptoms in patients with dementia were nighttime disturbances (38%), depression (29%) and aberrant motor behaviour (28%) and the most distressing symptoms for nursing staff were delusions, aggression and nighttime disturbances. The overall frequency of BPSD increased from 67% in mild dementia, to 76% in moderate dementia and to 88% in severe dementia. The most frequent symptoms in patients without dementia were depression (19%), nighttime disturbances (13%) and irritability (13%). The most distressing symptoms were aggression and delusions, while the same symptoms were consistently rated as less distressing than in patients with dementia. Factor analysis revealed three independent groups of BPSD that explained 45% of the total variance. First, expansive symptoms (aggression, irritability, nighttime disturbances, aberrant motor behaviour and disinhibition) were frequent, distressing for nursing staff and associated with many complications. Second, psychotic symptoms (delusions and hallucinations) were infrequent, distressing and associated with some complications. Third, affective symptoms (apathy, anxiety and depression) were frequent, non-distressing and associated with few complications. The results did not change when cases with delirium were excluded from both groups.

conclusionsBPSD are common in older hospital patients with dementia and associated with considerable distress in nursing staff, as well as a wide range of special treatments needs and additional behavioural and medical complications. Management strategies are needed to improve the situation for both patients and hospital staff.

Indexed as

Quality of Health CareAgedAged, 80 and overAnxietyBehaviorBehavioral SymptomsCross-Sectional StudiesDelusionsDementiaDepressionFemaleGermanyHospitals, GeneralHumansInpatientsIrritable MoodAcute hospitalbehavioural and psychological symptoms of dementiaBPSD

Identifiers

PMID28065176
PMCPMC6998873
OpenAlexW2569225332

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.