Evidence map›Paper›PMID 28064552›Full record

ArticlePharmaceutical biology2017

The novel role of β-aescin in attenuating CCl

Harsimran Singh, Shabir Sidhu, Kanwaljit Chopra, M U Khan

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Harsimran Singha Department of Research, Innovations & Consultancy , IKG Punjab Technical University , Kapurthala , Punjab , India.
Shabir Sidhuc Department of Life Sciences , Punjab Institute of technology, IKG Punjab Technical University , Kapurthala , Punjab , India.
Kanwaljit Choprad Pharmacology Research Laboratory , University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Punjab University , Chandigarh , India.
M U Khanb Sri Sai College of Pharmacy, Badhani , Pathankot , Punjab , India.
Sri Sai University · INPunjab Technical University · INUniversity of the Punjab · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextβ-Aescin has anti-inflammatory, anti-oxidant and antiedematous properties.

objectiveThe present study investigated the hepatoprotective effect and underlying mechanisms of β-aescin in CCl MATERIALS AND

methodsThirty-five Wistar rats were divided into six groups: normal control, CCl

resultsβ-Aescin (3.6 mg/kg) markedly decreased CCl DISCUSSION AND

conclusionThe findings suggest that β-aescin has a protective effect on CCl

Indexed as

AnimalsCarbon TetrachlorideChemical and Drug Induced Liver InjuryCollagenEscinFemaleGlutathioneLipid PeroxidationLiverMaleRatsRats, WistarTransforming Growth Factor beta1Carbon TetrachlorideCollagenEscinGlutathioneTransforming Growth Factor beta1Aesculus hippocastanumantifibroticCarbon tetrachloridenitrosative stressoxidative stressSilymarin

Identifiers

PMID28064552
PMCPMC6130713
OpenAlexW2571052819

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.