Evidence map›Paper›PMID 28064475›Full record

ArticleThe world journal of men's health2017

Administration of Goji (Lycium chinense Mill.) Extracts Improves Erectile Function in Old Aged Rat Model.

Hyong Woo Moon, Jung Woo Park, Kyu Won Lee, Hyun Cheol Jeong, Jin Bong Choi, Sae Woong Choi, Woong Jin Bae, Hyuk Jin Cho, U Syn Ha, Sung Hoo Hong and 3 more

Open access · diamondAbstract read
In one paragraph

Article in The world journal of men's health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Biomolecules · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Efficacy and Safety of a Mixed Extract ofThe world journal of men's health · 2018
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hyong Woo MoonDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jung Woo ParkDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kyu Won LeeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hyun Cheol JeongDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jin Bong ChoiDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sae Woong ChoiDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Woong Jin BaeDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hyuk Jin ChoDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
U Syn HaDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sung Hoo HongDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jeong Ho GeumBiomix Inc., Goyang, Korea.
Seong Bin HongBiomix Inc., Goyang, Korea.
Sae Woong KimDepartment of Urology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Catholic University of Korea · KRKorea Aerospace University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigated the effect of goji (Lycium chinense Mill.) on erectile dysfunction in old-aged rats. MATERIALS AND

methodsTwenty-four 18-month-old male Sprague-Dawley rats (defined as old-aged rats) were used. Treatment groups contained eight rats each: a control group, goji extract of 150 mg/kg/day group, and goji extract of 300 mg/kg/day group. Treatment was by orogastric tube once daily for 6 weeks. After 6 weeks of treatment, testes weight, serum testosterone, superoxide dismutase, nitric oxide (NO)-cyclic guanosine monophosphate (cGMP)-related parameters, intracavernous pressure/mean arterial pressure, and histological changes were examined.

resultsTreatments with goji extracts increased serum testosterone level, increased the expression of endothelial NO synthase, neuronal NO synthase, and cGMP, improved the oxidative stress marker, and decreased corporal fibrosis.

conclusionsOur results indicate that goji extract may have a positive effect on erectile dysfunction via its antioxidant effects.

Indexed as

AntioxidantsErectile dysfunctionTestosterone

Identifiers

PMID28064475
PMCPMC5419117
OpenAlexW2577975471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.