Evidence map›Paper›PMID 28064371›Full record

Observational studyObesity surgery2017

Thrombin Generation Measurements in Patients Scheduled for Laparoscopic Bariatric Surgery.

Jérémie Thereaux, Fanny Mingant, Charles Roche, Hubert Galinat, Francis Couturaud, Karine Lacut

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jérémie ThereauxDepartment of General, Digestive and Metabolic Surgery, La Cavale Blanche University Hospital, Boulevard Tanguy Prigent, 29200, Brest, France. jeremie.thereaux@chu-brest.fr.
Fanny MingantUniversity of Bretagne Occidentale (UBO), EA 3878 (GETBO), 22 Avenue Camille Desmoulins, CS 93837-29238, Brest, France.
Charles RocheDepartment of General, Digestive and Metabolic Surgery, La Cavale Blanche University Hospital, Boulevard Tanguy Prigent, 29200, Brest, France.
Hubert GalinatUniversity of Bretagne Occidentale (UBO), EA 3878 (GETBO), 22 Avenue Camille Desmoulins, CS 93837-29238, Brest, France.
Francis CouturaudUniversity of Bretagne Occidentale (UBO), EA 3878 (GETBO), 22 Avenue Camille Desmoulins, CS 93837-29238, Brest, France.
Karine LacutUniversity of Bretagne Occidentale (UBO), EA 3878 (GETBO), 22 Avenue Camille Desmoulins, CS 93837-29238, Brest, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObese patients are known to be in an in vitro hypercoagulable state relative to normal-weight patients. Our study aimed to identify markers of enhanced coagulability (endogenous thrombin potential (ETP)) in morbidly obese patients using the thrombin generation (TG) test. MATERIALS AND

methodsAll patients scheduled for laparoscopic bariatric surgery (LBS) between September 1, 2014 and January 31, 2016 were eligible for our prospective study. We used logistic regression to compute the odds ratio (OR) across ETP quartile distributions to evaluate the risk of enhanced TG.

resultsWe studied 102 patients, 77.5% were female, mean age was 41.2 ± 12.1 years, and mean BMI was 45.5 ± 7.0 k/m

conclusionsOur study highlights the role of total cholesterol and blood inflammatory marker levels in enhancing ETP in morbidly obese patients. Further studies are necessary to confirm the decreased ETP following LBS with the expected reduced inflammatory marker and total cholesterol levels.

Indexed as

Bariatric SurgeryBlood Coagulation TestsAdultBiomarkersFemaleHumansLaparoscopyMaleMiddle AgedObesity, MorbidProspective StudiesRisk FactorsThrombinThrombophiliaBiomarkersThrombinLow grade inflammationMorbid obesityThrombin generation

Identifiers

PMID28064371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.