Evidence map›Paper›PMID 28064219›Full record

ArticleIn vivo (Athens, Greece)2017

Active and Passive Immunization Against Staphylococcus aureus Periprosthetic Osteomyelitis in Rats.

Niels H Søe, Nina Vendel Jensen, Asger Lundorff Jensen, Janne Koch, Steen Seier Poulsen, Gerald B Pier, Helle Krogh Johansen

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Staphylococcal Biofilms.Microbiology spectrum · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Niels H SøeHand Section, Department of Orthopaedics, Herlev and Gentofte University Hospital, Hellerup, Denmark Niels.Soee.Nielsen@regionh.dk.
Nina Vendel JensenDepartment of Anaesthesiology, Intensive Care and Operations, Herlev and Gentofte University Hospital, Hellerup, Denmark.
Asger Lundorff JensenBiochemical Department, Faculty of Life Science, University of Copenhagen, Copenhagen, Denmark.
Janne KochDepartment of Experimental Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark.
Steen Seier PoulsenBiomedical Department, Panum Institute, University of Copenhagen, Copenhagen, Denmark.
Gerald B PierDivision of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, U.S.A.
Helle Krogh JohansenDepartment of Clinical Microbiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
University of Copenhagen · DKGentofte Hospital · DKNovo Nordisk Foundation · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimStaphylococcus aureus infection associated with orthopedic implants cannot always be controlled. We used a knee prosthesis model with implant-related osteomyelitis in rats to explore induction of an effective immune response with active and passive immunization. MATERIALS AND

methodsFifty-two Sprague-Dawley rats were divided into active (N=28) and passive immunization groups (N=24). A bacterial inoculum of 10 RESULTS/

conclusionActive immunization against PNAG significantly reduced the consequences of osteomyelitis infection from PNAG-producing intercellular adhesion (ica

Indexed as

AnimalsBiomarkersImmunizationMaleOsteomyelitisPeriprosthetic FracturesRabbitsRatsRats, Sprague-DawleyStaphylococcal InfectionsStaphylococcus aureusBiomarkersica+ strainica− strainimmunizationimplant-related infection Staphylococcus aureusOsteomyelitisvaccine

Identifiers

PMID28064219
PMCPMC5354146
OpenAlexW2576860286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.