Evidence map›Paper›PMID 28063650›Full record

ReviewThe Journal of investigative dermatology2017

Performing Skin Microbiome Research: A Method to the Madness.

Heidi H Kong, Björn Andersson, Thomas Clavel, John E Common, Scott A Jackson, Nathan D Olson, Julia A Segre, Claudia Traidl-Hoffmann

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in The Journal of investigative dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03584360 (Study Role of the Local Treatments on the Microbiome Modulation in the Psoriatic Skin. Study Monocentric, Interventional, Randomized and Single-blind), which is not on this map. Cited by 107 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 2 pooled it
20.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03584360 phase2completednot on this mapstarted 2018, after this paper: background citation

Study Role of the Local Treatments on the Microbiome Modulation in the Psoriatic Skin. Study Monocentric, Interventional, Randomized and Single-blind

TypeinterventionalSponsorCentre Hospitalier Universitaire de NiceRan2018 to 2019Enrolled30ConditionsPsoriasis VulgarisArmsBetamethasone-Calcipotriene Topical
3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 2 syntheses or guidelines pooled it, 225 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin.JID innovations : skin science from molecules to population health · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Skin microbiome and dermatologic disorders.The Journal of clinical investigation · 2025
    Review
  15. Article
  16. Plasma Treatment - Results of Skin Microbiome Analysis.Clinical, cosmetic and investigational dermatology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Effective use of skin microbiome signatures for fingerprint identification.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 5 countries.

Heidi H KongDermatology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland, USA. Electronic address: konghe@mail.nih.gov.
Björn AnderssonDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Thomas ClavelCore Facility NGS/Microbiome, ZIEL Institute for Food and Health, Technical University of Munich, Freising, Germany.
John E CommonInstitute of Medical Biology, A*STAR, Singapore.
Scott A JacksonBiosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, Maryland, USA.
Nathan D OlsonBiosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, Maryland, USA.
Julia A SegreTranslational and Functional Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA.
Claudia Traidl-HoffmannInstitute of Environmental Medicine, UNIKA-T, Technical University of Munich and Helmholtz Zentrum München-German Research Center for Environmental Health, Augsburg, Germany; Christine Kühne Center for Allergy Research and Education, Davos, Switzerland.
National Institute of Standards and Technology · USAgency for Science, Technology and Research · SGCenter for Environmental Health · USKarolinska Institutet · SELeibniz-Institute for Food Systems Biology at the Technical University of Munich · DENational Cancer Institute · USNational Human Genome Research Institute · US

Funding

Gene-Environment Interactions at the Skin SurfaceZIAHG000180 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI SEGRE, JULIA ANGELA · 2009 to 2025
$29.6M
Effects of systemic and topical perturbations on human microbesZIABC011558 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KONG, HEIDI · 2014 to 2021
$6.9M
Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis PatientsZIABC010938 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KONG, HEIDI · 2009 to 2021
$5.4M
Intramural NIH HHS ZIA BC010938Intramural NIH HHS ZIA BC011558
6 · The paper itself

Abstract

Growing interest in microbial contributions to human health and disease has increasingly led investigators to examine the microbiome in both healthy skin and cutaneous disorders, including acne, psoriasis, and atopic dermatitis. The need for common language, effective study design, and validated methods is critical for high-quality standardized research. Features, unique to skin, pose particular challenges when conducting microbiome research. This review discusses microbiome research standards and highlights important factors to consider, including clinical study design, skin sampling, sample processing, DNA sequencing, control inclusion, and data analysis.

Indexed as

DermatologyMicrobiotaAcne VulgarisClinical Trials as TopicDermatitis, AtopicHumansPsoriasisResearch DesignSequence Analysis, DNASkinSkin Diseases

Identifiers

PMID28063650
PMCPMC5468751
OpenAlexW2568706414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.