Evidence map›Paper›PMID 28063241›Full record

ArticleAlcoholism, clinical and experimental research2017

Health Risk Factors Associated with Lifetime Abstinence from Alcohol in the 1979 National Longitudinal Survey of Youth Cohort.

William C Kerr, Camillia K Lui, Edwina Williams, Yu Ye, Thomas K Greenfield, E Anne Lown

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

William C KerrAlcohol Research Group, Public Health Institute, Emeryville, California.
Camillia K LuiAlcohol Research Group, Public Health Institute, Emeryville, California.
Edwina WilliamsAlcohol Research Group, Public Health Institute, Emeryville, California.
Yu YeAlcohol Research Group, Public Health Institute, Emeryville, California.
Thomas K GreenfieldAlcohol Research Group, Public Health Institute, Emeryville, California.ORCID 0000-0002-3108-4812
E Anne LownAlcohol Research Group, Public Health Institute, Emeryville, California.

Funding

TREND &STRUCTURE OF ALCOHOL DEPENDENCE--GENERAL POPULATION 1990 SURVEY DATAP50AA005595 · NIAAA · WESTERN CONSORTIUM FOR PUBLIC HEALTH · PI MULIA, NINA · 1985 to 2025
$34.1M
Inter-Relationships Between Life-Course Alcohol Patterns and Health ConditionsR01AA021448 · NIAAA · PUBLIC HEALTH INSTITUTE · PI KERR, WILLIAM C. · 2014 to 2017
$1.6M
NIAAA NIH HHS P50 AA005595NIAAA NIH HHS R01 AA021448
6 · The paper itself

Abstract

backgroundThe choice and definition of a comparison group in alcohol-related health studies remains a prominent issue in alcohol epidemiology due to potential biases in the risk estimates. The most commonly used comparison group has been current abstainers; however, this includes former drinkers who may have quit drinking due to health problems. Lifetime abstention could be the best option, but measurement issues, selection biases due to health and other risk factors, and small numbers in populations are important concerns. This study examines characteristics of lifetime abstention and occasional drinking that are relevant for alcohol-related health studies.

methodsThis study used data from the National Longitudinal Survey of Youth 1979 cohort of 14 to 21 year olds followed through 2012 (n = 7,515). Definitions of abstinence and occasional drinking were constructed based on multiple measurements. Descriptive analyses were used to compare the definitions, and in further analysis, lifetime abstainers (n = 718) and lifetime minimal drinkers (n = 1,027) were compared with drinkers across demographics and early-life characteristics (i.e., religion, poverty, parental education, and family alcohol problems) in logistic regression models.

resultsUsing a strict measurement of zero drinks from adolescence to the 50s, only 1.7% of the sample was defined as lifetime abstainer compared to a broader definition allowing a total of 1 drink over the lifetime that included 9.5% and to lifetime minimal drinking (a total of 3 drinks or less a month), which accounted for 13.7%. Factors significantly associated with lifetime abstention and lifetime minimal drinking included religion, poverty, having no family alcohol problems, Hispanic ethnicity, foreign-born, and female gender. Importantly, work-related health limitations in early life were significantly associated, but not childhood physical and mental health problems.

conclusionsAlcohol-related health studies should utilize lifetime classifications of drinkers and abstainers, and, in doing so, should account for early-life socioeconomic adversity and childhood health factors or consider these as unmeasured confounders.

Indexed as

Alcohol AbstinenceAdolescentAdultAlcohol DrinkingAlcoholismChild HealthCohort StudiesFamilyFemaleHealth SurveysHispanic or LatinoHumansLongitudinal StudiesMaleMiddle AgedPovertyAbstainerAlcoholEarly LifeHealthLife Course

Identifiers

PMID28063241
PMCPMC5272800

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.