Evidence map›Paper›PMID 28063168›Full record

ReviewPhotochemistry and photobiology2017

Phytochemicals for the Prevention of Photocarcinogenesis.

Mary K Montes de Oca, Ross L Pearlman, Sarah F McClees, Rebecca Strickland, Farrukh Afaq

Open access · bronzeAbstract readReview
In one paragraph

Review in Photochemistry and photobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. A ProprietaryAntioxidants (Basel, Switzerland) · 2025
    Article
  4. Frontiers in pharmacology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Polyphenols in Metabolic Diseases.Molecules (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Protective Effects and Mechanisms ofInternational journal of molecular sciences · 2019
    Article
  20. Tea polyphenols for the prevention of UVB-induced skin cancer.Photodermatology, photoimmunology & photomedicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mary K Montes de OcaDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL.
Ross L PearlmanDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL.
Sarah F McCleesDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL.
Rebecca StricklandDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL.
Farrukh AfaqDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, AL.
University of Alabama at Birmingham · US

Funding

Combinatorial Approach for Reducing Invasive Potential of Melanoma CellsR21CA173043 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AFAQ, FARRUKH · 2013 to 2014
$346k
NCI NIH HHS R21 CA173043
6 · The paper itself

Abstract

Ultraviolet (UV) exposure has an array of damaging effects and is the main cause of skin cancer in humans. Nonmelanoma skin cancer (NMSC), including basal cell carcinoma and squamous cell carcinoma, is the most common type of cancer. Incidence of NMSC has increased due to greater UV radiation, increased life expectancy and other changes in lifestyle; the annual cost of skin cancer treatment in the United States has increased concurrently to around eight billion dollars. Because of these trends, novel approaches to skin cancer prevention have become an important area of research to decrease skin cancer morbidity and defray the costs associated with treatment. Chemoprevention aims to prevent or delay the development of skin cancer through the use of phytochemicals. Use of phytochemicals as chemopreventive agents has gained attention due to their low toxicity and anticarcinogenic properties. Phytochemicals also exhibit antioxidant, anti-inflammatory and antiproliferative effects which support their use as chemopreventive agents, particularly for skin cancer. Preclinical and human studies have shown that phytochemicals decrease UV-induced skin damage and photocarcinogenesis. In this review article, we discuss the selected phytochemicals that may prevent or delay UV-induced carcinogenesis and highlight their potential use for skin protection.

Indexed as

AnimalsAntineoplastic Agents, PhytogenicChemopreventionDNADNA DamageHumansInflammationNeoplasms, Radiation-InducedReactive Oxygen SpeciesSignal TransductionSkinSkin NeoplasmsUltraviolet RaysAntineoplastic Agents, PhytogenicDNAReactive Oxygen Species

Identifiers

PMID28063168
PMCPMC5500428
OpenAlexW2569584966

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.