ArticleThe journal of headache and pain2017
The relationship between right-to-left shunt and brain white matter lesions in Japanese patients with migraine: a single center study.
Article in The journal of headache and pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Evaluating the relationship between right-to-left shunt and white matter hyperintensities in migraine patients: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Patent foramen ovale is associated with white matter hyperintensities in young adults: a case-control study.Frontiers in neurology · 2026Article
- [Multiple comorbidities with migraine-Is there a common cause?]Schmerz (Berlin, Germany) · 2025Review
- White matter hyperintensity burden in young patent foramen ovale patients and its correlation with migraine.Frontiers in neurology · 2025Article
- Hallmarks of primary headache: part 1 - migraine.The journal of headache and pain · 2024Review
- Right-to-left shunt-associated brain functional changes in migraine: evidences from a resting-state FMRI study.Frontiers in human neuroscience · 2024Article
- Relationship between right-to-left shunt and white matter lesions in patients with migraine: a single-center study.Frontiers in neurology · 2024Article
- The Influence of Patent Foramen Ovale on the Clinical Features of Migraine without Aura: A Cross-Sectional Study.International journal of general medicine · 2023Article
- The Patent Foramen Ovale and Migraine: Associated Mechanisms and Perspectives from MRI Evidence.Brain sciences · 2022Review
- Small Demyelination of the Cortex May Be a Potential Marker for the Right-to-Left Shunt of the Heart.Brain sciences · 2022Article
- Right-to-left shunts in unexplained syncope: an age- and sex-matched case-control study.Quantitative imaging in medicine and surgery · 2022Article
- Diffusion tensor magnetic resonance imaging: is it valuable in the detection of brain microstructural changes in patients having migraine without aura?Polish journal of radiology · 2021Article
- Assessment of gray and white matter structural alterations in migraineurs without aura.The journal of headache and pain · 2017Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere may be a link between right-to-left shunt (RLs) and brain white matter lesions (WMLs) in patients with migraine. In this study, we assessed the relationship between WMLs and RLs in Japanese migraine patients.
methodsA total of 107 consecutive patients with migraine with (MA) and without aura (MWOA) were included in this study. Contrast transcranial Doppler ultrasound was used to detect RLs. WMLs were graded using brain magnetic resonance imaging based on well-established criteria.
findingsThe prevalence of RLs was significantly increased in the WMLs positive group (n = 24) compared with the WMLs negative group (n = 83) (75.0% vs. 47.0%, p = 0.015). In prevalence of WMLs between MA and MWOA patients, there were no statistical differences (p = 0.410). Logistic regression analysis adjusted by age and disease duration of migraine identified an RLs-positive status as the sole determinant for the presence of WMLs (OR = 6.15; 95% CI 1.82-20.8; p = 0.003)
conclusionOur study suggests a possible link between RLs and WMLs in Japanese patients with migraine.
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