Evidence map›Paper›PMID 28062578›Full record

ArticleThe Journal of biological chemistry2017

GMP Synthase Is Required for Virulence Factor Production and Infection by

Jessica L Chitty, Tayla L Tatzenko, Simon J Williams, Y Q Andre E Koh, Elizabeth C Corfield, Mark S Butler, Avril A B Robertson, Matthew A Cooper, Ulrike Kappler, Bostjan Kobe and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Naringin from Coffee Inhibits FoodborneMolecules (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. The Journal of biological chemistry · 2017
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jessica L ChittyFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
Tayla L TatzenkoFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
Simon J WilliamsFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
Y Q Andre E KohFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
Elizabeth C CorfieldFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
Mark S Butlerthe Institute for Molecular Bioscience, and.
Avril A B Robertsonthe Institute for Molecular Bioscience, and.
Matthew A CooperFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
Ulrike KapplerFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
Bostjan KobeFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences.
James A FraserFrom the Australian Infectious Diseases Research Centre, School of Chemistry & Molecular Biosciences, jafraser@uq.edu.au.
AgriBio · AUUniversity of Queensland · AUAustralian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last four decades the HIV pandemic and advances in medical treatments that also cause immunosuppression have produced an ever-growing cohort of individuals susceptible to opportunistic pathogens. Of these, AIDS patients are particularly vulnerable to infection by the encapsulated yeast

Indexed as

Carbon-Nitrogen LigasesCryptococcosisCryptococcus neoformansEnzyme InhibitorsGenes, FungalVirulence FactorsCarbon-Nitrogen LigasesEnzyme InhibitorsGMP synthase (glutamine-hydrolyzing)Virulence Factorsenzyme kineticsfungiGMP synthasenucleoside/nucleotide biosynthesispurinevirulence factor

Identifiers

PMID28062578
PMCPMC5314198
OpenAlexW2570203573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.