Evidence map›Paper›PMID 28062568›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Renal Collectrin Protects against Salt-Sensitive Hypertension and Is Downregulated by Angiotensin II.

Pei-Lun Chu, Joseph C Gigliotti, Sylvia Cechova, Gabor Bodonyi-Kovacs, Fang Chan, Donna Lee Ralph, Nancy Howell, Kambiz Kalantari, Alexander L Klibanov, Robert M Carey and 2 more

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Collectrin (American journal of physiology. Renal physiology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Pei-Lun ChuDivision of Nephrology.
Joseph C GigliottiDivision of Nephrology.
Sylvia CechovaDivision of Nephrology.
Gabor Bodonyi-KovacsDivision of Nephrology.
Fang ChanDivision of Nephrology.
Donna Lee RalphDepartment of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California.
Nancy HowellDivision of Endocrinology, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.
Kambiz KalantariDivision of Nephrology.
Alexander L KlibanovCardiovascular Division, and.
Robert M CareyDivision of Endocrinology, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia.
Alicia A McDonoughDepartment of Cell and Neurobiology, University of Southern California, Keck School of Medicine, Los Angeles, California.
Thu H LeDivision of Nephrology, THL4T@virginia.edu.
University of Southern California · USUniversity of Virginia Health System · USLiberty University · US

Funding

Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI PATEL, UPTAL D · 2012 to 2016
$5.9M
Sodium transporter regulation during hypertensionR01DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AURELIE EDWARDS, Alicia A. McDonough · 2011 to 2026
$5.8M
Kidney Disease and InflammationT32DK072922 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2006 to 2020
$2.6M
GSTM1, APOL1, and their joint contribution to severity of hypertension and chronic kidney diseaseR01DK094907 · NIDDK · UNIVERSITY OF VIRGINIA · PI LE, THU H., MYCHALECKYJ, JOSYF · 2012 to 2021
$1.7M
Sodium-chloride co-transporter regulation in the kidneyR56DK083785 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCDONOUGH, ALICIA A., YU, ALAN S · 2010 to 2010
$173k
NIDDK NIH HHS P30 DK096493NIDDK NIH HHS R01 DK083785NIDDK NIH HHS R01 DK094907NIDDK NIH HHS R56 DK083785NIDDK NIH HHS T32 DK072922
6 · The paper itself

Abstract

Collectrin, encoded by the

Indexed as

Down-RegulationAngiotensin IIAnimalsHypertensionKidneyMaleMembrane GlycoproteinsMiceMice, KnockoutSodium Chloride, DietaryAngiotensin IIMembrane GlycoproteinsSodium Chloride, DietaryTmem27 protein, mouseangiotensin converting enzymecollectrinhypertensionsalt sensitivityTmem27

Identifiers

PMID28062568
PMCPMC5461790
OpenAlexW2571175246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.