Evidence map›Paper›PMID 28062553›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2017

Neurobrucellosis: Unexpected Answer From Metagenomic Next-Generation Sequencing.

Kanokporn Mongkolrattanothai, Samia N Naccache, Jeffrey M Bender, Erik Samayoa, Elizabeth Pham, Guixia Yu, Jennifer Dien Bard, Steve Miller, Grace Aldrovandi, Charles Y Chiu

Abstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kanokporn MongkolrattanothaiDepartment of Pediatrics, Division of Infectious Diseases.
Samia N NaccacheDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles.
Jeffrey M BenderDepartment of Pediatrics, Division of Infectious Diseases.
Erik SamayoaDepartment of Laboratory Medicine.
Elizabeth PhamDepartment of Laboratory Medicine.
Guixia YuDepartment of Laboratory Medicine.
Jennifer Dien BardDepartment of Pathology and Laboratory Medicine, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles.
Steve MillerDepartment of Laboratory Medicine.
Grace AldrovandiDepartment of Pediatrics, Division of Infectious Diseases.
Charles Y ChiuDepartment of Laboratory Medicine.

Funding

Childrens Hospital Los Angeles Child Health Research Development AwardK12HD052954 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI WILLIAMS, ROBERTA GAY · 2006 to 2017
$4.0M
6 · The paper itself

Abstract

A diagnosis of brucellosis can be difficult because routine culture and serological methods exhibit variable sensitivity and specificity. We present the use of a metagenomic next- generation sequencing assay to diagnose a case of neurobrucellosis from cerebrospinal fluid, resulting in the institution of appropriate antibiotic treatment and a favorable clinical outcome.

Indexed as

BrucellaBrucellosisChildFemaleHigh-Throughput Nucleotide SequencingHumansMagnetic Resonance ImagingMetagenomicsSpinal Corddiagnostic microbiologyencephalitismeningitismetagenomic next-generation sequencingneurobrucellosis

Identifiers

PMID28062553
PMCPMC6251619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.