Evidence map›Paper›PMID 28061860›Full record

ArticleBMC research notes2017

Preliminary investigation of the transmission of tuberculosis between farmers and their cattle in smallholder farms in northwestern Ethiopia: a cross-sectional study.

Anwar Nuru, Gezahegne Mamo, Aboma Zewude, Yitayal Mulat, Gashaw Yitayew, Aschalew Admasu, Girmay Medhin, Rembert Pieper, Gobena Ameni

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 6 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 6 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  15. Occupational exposure and challenges in tackling M. bovis at human-animal interface: a narrative review.International archives of occupational and environmental health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Anwar NuruAklilu Lemma Institute of Pathobiology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia. hamduanwar@yahoo.com.
Gezahegne MamoCollege of Veterinary Medicine and Agriculture, Addis Ababa University, P.O. Box 34, Debre Zeit, Ethiopia.
Aboma ZewudeAklilu Lemma Institute of Pathobiology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.
Yitayal MulatFelegehiwot Comprehensive Specialized Hospital, P. O. Box: 47, Bahir Dar, Ethiopia.
Gashaw YitayewBahir Dar Regional Health Research Laboratory Centre, P.O. Box 641, Bahir Dar, Ethiopia.
Aschalew AdmasuBahir Dar Regional Health Research Laboratory Centre, P.O. Box 641, Bahir Dar, Ethiopia.
Girmay MedhinAklilu Lemma Institute of Pathobiology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.
Rembert PieperJ. Craig Venter Institute, 9704 Medical Center Drive, Rockville, MD, USA.
Gobena AmeniAklilu Lemma Institute of Pathobiology, Addis Ababa University, P.O. Box 1176, Addis Ababa, Ethiopia.
Addis Ababa University · ETBahir Dar University · ETJ. Craig Venter Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe feeding habits and close physical contact between Ethiopian farmers and their cattle promote the transmission of tuberculosis (TB) between the farmers and their cattle. This study aimed to investigate the transmission of TB between farmers and their cattle in smallholder farms in northwestern Ethiopia.

resultsA total of 70 human TB lymphadenitis (TBLN) cases visiting the Felegehiwot Comprehensive Specialized Hospital in Bahir Dar City and 660 cattle were investigated. Half of the cattle were owned by households with TB cases, and the remaining half by TB free households. Among the 70 human TBLN patients interviewed, 65.7% (46 out of 70) of the respondents were not aware of zoonotic TB, and 67.1% (47/70) of them consumed raw milk. Positive cultures of TB were obtained in 40 of the 70 cases where TBLN tests were positive with fine needle aspiration cytology. Spoligotyping resulted in 31 different patterns, of which 25 isolates were Mycobacterium (M.) tuberculosis, and the remaining were M. africanum (4 isolates) and M. bovis (2 isolates). None of the animals showed positive test results for bovine TB by comparative intradermal tuberculin test.

conclusionsBased on the identification of M. bovis from two patients diagnosed with TBLN, we obtained preliminary evidence of zoonotic transmission of TB in northwestern Ethiopia. We did not identify a direct route of transmission between cattle and its owners. This is the objective of further investigations.

Indexed as

FarmersAnimalsBiopsy, Fine-NeedleCattleCross-Sectional StudiesEthiopiaFood ContaminationFood MicrobiologyHumansMycobacterium bovisOccupational ExposureTuberculinTuberculosisTuberculosis, BovineTuberculosis, Lymph NodeZoonosesTuberculinCattleFarmerMycobacterium bovisTransmissionTuberculous lymphadenitis

Identifiers

PMID28061860
PMCPMC5219749
OpenAlexW2570974006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.