ArticleJournal of nanobiotechnology2017
Cytotoxic effects of nanosilver are highly dependent on the chloride concentration and the presence of organic compounds in the cell culture media.
Article in Journal of nanobiotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 58 citations in OpenAlex.
- KCa3.1 mediates radioresistance of silver nanoparticles in human glioblastoma cells.Pflugers Archiv : European journal of physiology · 2026Article
- Increased Cytotoxicity of Bimetallic Ultrasmall Silver-Platinum Nanoparticles (2 nm) on Cells and Bacteria in Comparison to Silver Nanoparticles of the Same Size.Materials (Basel, Switzerland) · 2024Article
- Respiration and growth ofMicrobiology spectrum · 2024Article
- Organic Electronic Platform for Real-Time Phenotypic Screening of Extracellular-Vesicle-Driven Breast Cancer Metastasis.Advanced healthcare materials · 2023Article
- Comparative in vivo toxicokinetics of silver powder, nanosilver and soluble silver compounds after oral administration to rats.Archives of toxicology · 2023Article
- Article
- Biofilm Inhibitory Activity of Actinomycete-Synthesized AgNPs with Low Cytotoxic Effect: Experimental and In Silico Study.Microorganisms · 2022Article
- Antibacterial and Cytocompatible: Combining Silver Nitrate with Strontium Acetate Increases the Therapeutic Window.International journal of molecular sciences · 2022Article
- Use of an in silico knowledge discovery approach to determine mechanistic studies of silver nanoparticles-induced toxicity from in vitro to in vivo.Particle and fibre toxicology · 2022Article
- U.S. Federal Agency interests and key considerations for new approach methodologies for nanomaterials.ALTEX · 2022Article
- Risk assessment on-a-chip: a cell-based microfluidic device for immunotoxicity screening.Nanoscale advances · 2021Article
- Characterization, bio-uptake and toxicity of polymer-coated silver nanoparticles and their interaction with human peripheral blood mononuclear cells.Beilstein journal of nanotechnology · 2021Article
- Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model.Nanomaterials (Basel, Switzerland) · 2020Article
- Competitive Surface Colonization of Antibacterial and Bioactive Materials Doped with Strontium and/or Silver Ions.Nanomaterials (Basel, Switzerland) · 2020Article
- Silver-Containing Titanium Dioxide Nanocapsules for Combating Multidrug-Resistant Bacteria.International journal of nanomedicine · 2020Article
- New Look on Antifungal Activity of Silver Nanoparticles (AgNPs).Polish journal of microbiology · 2019Article
- Revealing the Importance of Aging, Environment, Size and Stabilization Mechanisms on the Stability of Metal Nanoparticles: A Case Study for Silver Nanoparticles in a Minimally Defined and Complex Undefined Bacterial Growth Medium.Nanomaterials (Basel, Switzerland) · 2019Article
- Synthesis and biological characterization of alloyed silver-platinum nanoparticles: from compact core-shell nanoparticles to hollow nanoalloys.RSC advances · 2018Article
- Article
- A reversible fluorescent probe for monitoring Ag(I) ions.Journal of the Royal Society, Interface · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNanosilver shows great promise for use in industrial, consumer or medical products because of its antimicrobial properties. However, the underlying mechanisms of the effects of silver nanoparticles on human cells are still controversial. Therefore, in the present study the influence of the chloride concentration and different serum content of culture media on the cytotoxic effects of nanosilver was systematically evaluated.
resultsOur results show that nanosilver toxicity was strongly affected by the composition of the culture media. The chloride concentration, as well as the carbon content affected the silver agglomeration and the complex formation. But also the dissolution of nanosilver and the availability of free silver ions (Ag
conclusionsSilver coatings are used in health care products due to their bacteriostatic or antibacterial properties. The assessment of the toxicity of a certain compound is mostly done using in vitro assays. Therefore, cytotoxicity studies of nanosilver using human cell cultures have to be undertaken under well controlled and understood cultivations conditions in order to improve the compatibility of different studies. Especially when eukaryotic versus prokaryotic systems are compared for the evaluation of the use of nanosilver as antibacterial coatings for implants in order to prevent bacterial colonization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.