Evidence map›Paper›PMID 28061807›Full record

ArticleBMC cardiovascular disorders2017

Gender differences in sudden cardiac death in the young-a nationwide study.

Bo Gregers Winkel, Bjarke Risgaard, Thea Bjune, Reza Jabbari, Thomas Hadberg Lynge, Charlotte Glinge, Henning Bundgaard, Stig Haunsø, Jacob Tfelt-Hansen

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
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  3. Neuroticism and sudden cardiac death: a prospective cohort study from UK biobank.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
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  6. Autopsy of all young sudden death cases is important to increase survival in family members left behind.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
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  20. Development and assessment of a histopathological stability score for atheroma plaques.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Bo Gregers WinkelDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark. bowinkel@dadlnet.dk.
Bjarke RisgaardDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Thea BjuneDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Reza JabbariDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Thomas Hadberg LyngeDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Charlotte GlingeDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Henning BundgaardDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Stig HaunsøDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Jacob Tfelt-HansenDepartment of Cardiology, Copenhagen University Hospital, Rigshospitalet, 2142, Blegdamsvej 9, 2100, Copenhagen O, Denmark.
Rigshospitalet · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHitherto, sudden cardiac death (SCD) in the young has been described with no distinction between genders. SCD occurs more often in men (SCDm) than women (SCDw), but this disparity is not understood and has not been investigated systematically in a nationwide setting. Our objective was to report gender differences in SCD in the young in a nationwide (Denmark) setting.

methodsAll deaths in persons aged 1-35 years nationwide in Denmark between 2000 and 2009 were included. Death certificates and autopsy reports were obtained. The extensive health care registries in Denmark were used to investigate any known disease prior to death. SCDw were compared to SCDm.

resultsDuring the 10-year study period there were a total of 8756 deaths in 23.7 million person-years. In total, 635 deaths were SCD. SCDw constituted 205 deaths (32%). Women had a higher proportion of witnessed deaths (51 vs. 41%, p = 0.02) and died less often in a public place (16 vs. 26%, p = 0.01). Age at death, ratios of autopsies and sudden unexplained deaths, and comorbidities, did not differ. Causes of SCD were largely comparable between genders. The incidence rate of SCDw was half of that of SCDm (1.8 vs. 3.6 per 100,000 person-years, incidence rate ratio 2.0 (95% CI 1.7-2.4), p < 0.01).

conclusionsIncidence rate ratio of SCDm vs SCDw is 2. Young SCDw and SCDm are equally investigated, have comparable comorbidity, and causes of SCD. SCD due to potentially inherited cardiac diseases is less often in young women and could reflect a protection of female gender.

Indexed as

AdolescentAdultAge DistributionCause of DeathChildChild, PreschoolComorbidityDeath, Sudden, CardiacDenmarkFemaleHumansIncidenceInfantInfant, NewbornMaleRegistriesCauses of deathComorbidityEpidemiologyGenderRegistriesSCDSudden cardiac deathSudden deathYoung

Identifiers

PMID28061807
PMCPMC5219679
OpenAlexW2570412166

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.