Evidence map›Paper›PMID 28061552›Full record

ArticleJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses

The Role of Nursing Professionals in the Management of Patients With High-Risk Neuroblastoma Receiving Dinutuximab Therapy.

Rita Secola, Araz Marachelian, Susan L Cohn, Bonnie Toy, Kathleen Neville, Meaghan Granger, Angela Brentlinger, Gina Martin

Abstract read
In one paragraph

Article in Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rita Secola1 Children's Hospital Los Angeles, Los Angeles, CA, USA.
Araz Marachelian1 Children's Hospital Los Angeles, Los Angeles, CA, USA.
Susan L Cohn2 The University of Chicago Comer Children's Hospital, Chicago, IL, USA.
Bonnie Toy2 The University of Chicago Comer Children's Hospital, Chicago, IL, USA.
Kathleen Neville3 Arkansas Children's Hospital/University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Meaghan Granger4 Cook Children's Medical Center, Fort Worth, TX, USA.
Angela Brentlinger4 Cook Children's Medical Center, Fort Worth, TX, USA.
Gina Martin5 Washington University School of Medicine and St. Louis Children's Hospital, St. Louis, MO, USA.

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Fumito Ito · 1985 to 2026
$181.4M
NCI NIH HHS P30 CA014089
6 · The paper itself

Abstract

Neuroblastoma, an embryonic cancer of the sympathetic nervous system, is the most common extracranial solid tumor in childhood. Dinutuximab (formerly called ch14.18), a monoclonal antibody targeting the disialoganglioside GD2, has been shown to significantly improve survival rates in patients with high-risk neuroblastoma. However, the safe and effective use of dinutuximab therapy in these high-risk patients requires medical expertise in patient selection, treatment administration, and the monitoring and management of adverse events. Findings of the randomized phase III study (ANBL0032) led to the approval of dinutuximab for the treatment of children with high-risk neuroblastoma. Multi-institutional nursing approaches to implementing standard protocols ensure the effective management of high-risk neuroblastoma patients receiving dinutuximab immunotherapy. Understanding and implementing recommendations for the management of the clinically important and most common adverse events are essential to ensuring patient continuation of therapy and improving patient outcomes.

Indexed as

Nurse's RoleAntibodies, MonoclonalChildChild, PreschoolClinical Trials, Phase III as TopicHumansMaintenance ChemotherapyNeuroblastomaAntibodies, Monoclonaldinutuximabadverse eventsdinutuximabneuroblastomapediatric

Identifiers

PMID28061552
PMCPMC7523913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.