ArticleOncotarget2017
Cell type- and density-dependent effect of 1 T static magnetic field on cell proliferation.
Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 59 citations in OpenAlex.
- Magnetic Fields in Cancer Therapy: Mechanistic Insights, Signaling Pathways, and Evidence from Clinical and In Vitro Studies.Pharmaceutics · 2026Review
- Silent forces, hidden currents: the influence of static magnetic field stimulation on tumor biophysics.npj biomedical innovations · 2026Review
- A mathematical phase field model predicts superparamagnetic nanoparticle accelerated fusion of HeLa spheroids for field guided biofabrication.Scientific reports · 2025Article
- Cellular and Molecular Effects of Magnetic Fields.International journal of molecular sciences · 2024Review
- Magnetic Membranes for Cell Growth Under Curved and Reversible Deformations.Small science · 2024Article
- The Effect of Static Magnetic Fields of Different Strengths and Polarities on Cytokine Production by Human Lymphocytes In Vitro.Bioengineering (Basel, Switzerland) · 2024Article
- The Effect of a Rotating Magnetic Field on the Regenerative Potential of Platelets.International journal of molecular sciences · 2024Article
- Enhanced effect of X-rays in the presence of a static magnetic field within a 3D pancreatic cancer model.The British journal of radiology · 2023Article
- A novel magnetically controlled bioreactor for ex vivo expansion of NK-92 cells.Bioresources and bioprocessing · 2022Article
- Occupational exposure to electromagnetic fields in magnetic resonance environment: an update on regulation, exposure assessment techniques, health risk evaluation, and surveillance.Medical & biological engineering & computing · 2022Review
- Review
- Effect of High Static Magnetic Field (2 T-12 T) Exposure on the Mineral Element Content in Mice.Biological trace element research · 2021Article
- An upward 9.4 T static magnetic field inhibits DNA synthesis and increases ROS-P53 to suppress lung cancer growth.Translational oncology · 2021Article
- A Static Magnetic Field Improves Iron Metabolism and Prevents High-Fat-Diet/Streptozocin-Induced Diabetes.Innovation (Cambridge (Mass.)) · 2021Article
- Progressive Study on the Non-thermal Effects of Magnetic Field Therapy in Oncology.Frontiers in oncology · 2021Review
- Biopharmaceutical-Type Chinese Hamster Ovary Cell Cultivation Under Static Magnetic Field Exposure: A Study of Genotoxic Effect.Frontiers in bioengineering and biotechnology · 2021Article
- Combinatorial Effect of Magnetic Field and Radiotherapy in PDAC Organoids: A Pilot Study.Biomedicines · 2020Article
- Low-Frequency Magnetic Fields (LF-MFs) Inhibit Proliferation by Triggering Apoptosis and Altering Cell Cycle Distribution in Breast Cancer Cells.International journal of molecular sciences · 2020Article
- Effect of static magnetic field on DNA synthesis: The interplay between DNA chirality and magnetic field left-right asymmetry.FASEB bioAdvances · 2020Article
- Magnetic Susceptibility Difference-Induced Nucleus Positioning in Gradient Ultrahigh Magnetic Field.Biophysical journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing evidence shows that static magnetic fields (SMFs) can affect cell proliferation but mixed results have been reported. Here we systematically examined the effects of 1 T (Tesla) SMF, which is close to the SMF intensity that patients are exposed to MRI (magnetic resonance imaging) scanners in hospitals, for its effect on 15 different cell lines, including 12 human and 3 rodent cell lines. Our results show that 1 T SMF does not have apparent impact on cell cycle or cell death. However, at higher cell density, it reduced cell numbers in six out of seven solid human cancer cell lines. We found that both cell type and cell density had evident impacts on SMF effects. Moreover, the EGFR-Akt-mTOR pathway, which varies significantly between different cell types and densities, contributes to the differential effects of SMF. In addition, SMF also increases the efficacy of Akt inhibitors on cancer cell growth inhibition. Therefore 1 T SMF affects cell proliferation in a cell type- and cell density-dependent manner, and the inhibition effect of 1 T SMF on multiple cancer cells at higher cell density may indicate its clinical potential in late stage cancer therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.