Evidence map›Paper›PMID 28060564›Full record

ArticleCell adhesion & migration2017

Annexin A8 promotes VEGF-A driven endothelial cell sprouting.

Nicole Heitzig, Benjamin F Brinkmann, Sophia N Koerdt, Gonzalo Rosso, Victor Shahin, Ursula Rescher

Open access · goldAbstract read
In one paragraph

Article in Cell adhesion & migration, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. [Research progress of matrix stiffness in regulating endothelial cell sprouting].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2023
    Review
  5. Review
  6. Review
  7. The pathophysiological mechanisms underlying diabetic retinopathy.Frontiers in cell and developmental biology · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Annexins in Adipose Tissue: Novel Players in Obesity.International journal of molecular sciences · 2019
    Review
  12. Annexins in Translational Research: Hidden Treasures to Be Found.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nicole Heitziga Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Center , University of Münster , Münster , Germany.ORCID 0000-0003-1710-0406
Benjamin F Brinkmanna Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Center , University of Münster , Münster , Germany.
Sophia N Koerdta Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Center , University of Münster , Münster , Germany.ORCID 0000-0001-6392-8138
Gonzalo Rossob Institute of Physiology II , University of Münster , Münster , Germany.
Victor Shahinb Institute of Physiology II , University of Münster , Münster , Germany.
Ursula Reschera Institute of Medical Biochemistry, Center for Molecular Biology of Inflammation, and Interdisciplinary Clinical Research Center , University of Münster , Münster , Germany.
University of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physiological and pathological process of angiogenesis relies on orchestrated endothelial cell (EC) adhesion, migration and formation of new vessels. Here we report that human umbilical vein endothelial cells (HUVECs) deficient in Annexin A8 (AnxA8), a member of the annexin family of Ca

Indexed as

AnnexinsCell AdhesionEndothelial CellsExtracellular MatrixHumansHuman Umbilical Vein Endothelial CellsIntegrin beta1Multiprotein ComplexesNeovascularization, PathologicNeovascularization, PhysiologicSignal TransductionTetraspaninsVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2AnnexinsIntegrin beta1KDR protein, humanMultiprotein ComplexesTetraspaninsTSPAN1 protein, humanVascular Endothelial Growth Factor AVascular Endothelial Growth Factor Receptor-2angiogenesisAnnexin A8CD63endothelial cell sproutingHUVECinvasionproximity ligation assaytetraspaninVEGFR2β1 integrin

Identifiers

PMID28060564
PMCPMC5479451
OpenAlexW2570259633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.