Evidence map›Paper›PMID 28060265›Full record

ArticleJournal of visualized experiments : JoVE2016

Analysis of Cap-binding Proteins in Human Cells Exposed to Physiological Oxygen Conditions.

Sara Timpano, Gaelan Melanson, Sonia L Evagelou, Brianna D Guild, Erin J Specker, James Uniacke

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sara TimpanoDepartment of Molecular and Cellular Biology, University of Guelph.
Gaelan MelansonDepartment of Molecular and Cellular Biology, University of Guelph.
Sonia L EvagelouDepartment of Molecular and Cellular Biology, University of Guelph.
Brianna D GuildDepartment of Molecular and Cellular Biology, University of Guelph.
Erin J SpeckerDepartment of Molecular and Cellular Biology, University of Guelph.
James UniackeDepartment of Molecular and Cellular Biology, University of Guelph; juniacke@uoguelph.ca.
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Translational control is a focal point of gene regulation, especially during periods of cellular stress. Cap-dependent translation via the eIF4F complex is by far the most common pathway to initiate protein synthesis in eukaryotic cells, but stress-specific variations of this complex are now emerging. Purifying cap-binding proteins with an affinity resin composed of Agarose-linked m

Indexed as

Cell Culture TechniquesCulture MediaEukaryotic Initiation Factor-4FHumansOxygenProtein BiosynthesisRNA Cap-Binding ProteinsRNA CapsCulture MediaEukaryotic Initiation Factor-4FOxygenRNA Cap-Binding ProteinsRNA Caps

Identifiers

PMID28060265
PMCPMC5226629
OpenAlexW2564393448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.