Evidence map›Paper›PMID 28060254›Full record

ArticleJournal of visualized experiments : JoVE2016

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease.

Bruce M Damon, Ke Li, Richard D Dortch, E Brian Welch, Jane H Park, Amanda K W Buck, Theodore F Towse, Mark D Does, Daniel F Gochberg, Nathan D Bryant

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Magnetic Resonance Imaging Biomarkers of Muscle.Tomography (Ann Arbor, Mich.) · 2024
    Review
  5. Article
  6. Spin Lattice (T1) and Magnetization Transfer Saturation (MTDiagnostics (Basel, Switzerland) · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bruce M DamonInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University; Department of Biomedical Engineering, Vanderbilt University; Department of Molecular Physiology and Biophysics, Vanderbilt University; bruce.damon@vanderbilt.edu.
Ke LiInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University.
Richard D DortchInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University.
E Brian WelchInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University.
Jane H ParkInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University; Department of Molecular Physiology and Biophysics, Vanderbilt University.
Amanda K W BuckInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University.
Theodore F TowseInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University; Department of Physical Medicine and Rehabilitation, Vanderbilt University.
Mark D DoesInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University; Department of Biomedical Engineering, Vanderbilt University.
Daniel F GochbergInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University; Department of Physics and Astronomy, Vanderbilt University.
Nathan D BryantInstitute of Imaging Science, Vanderbilt University; Department of Radiology and Radiological Sciences, Vanderbilt University.
Vanderbilt University · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
Postdoctoral Training in Biomedical MRI and MRST32EB001628 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John C Gore · 2003 to 2026
$7.0M
Biophysical Basis of Muscle Functional MRIR01AR050101 · NIAMS · VANDERBILT UNIVERSITY · PI DAMON, BRUCE M. · 2005 to 2014
$3.1M
Multiparametric Classification of Muscle Damage in Inflammatory MyopathyR01AR057091 · NIAMS · VANDERBILT UNIVERSITY · PI DAMON, BRUCE M. · 2009 to 2013
$1.7M
Quantitative MRI of the Human Peripheral Nervous System In VivoK25EB013659 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DORTCH, RICHARD · 2012 to 2016
$750k
NCRR NIH HHS UL1 RR024975NIAMS NIH HHS R01 AR050101NIAMS NIH HHS R01 AR057091NIBIB NIH HHS K25 EB013659NIBIB NIH HHS T32 EB001628
6 · The paper itself

Abstract

Quantitative magnetic resonance imaging (qMRI) describes the development and use of MRI to quantify physical, chemical, and/or biological properties of living systems. Neuromuscular diseases often exhibit a temporally varying, spatially heterogeneous, and multi-faceted pathology. The goal of this protocol is to characterize this pathology using qMRI methods. The MRI acquisition protocol begins with localizer images (used to locate the position of the body and tissue of interest within the MRI system), quality control measurements of relevant magnetic field distributions, and structural imaging for general anatomical characterization. The qMRI portion of the protocol includes measurements of the longitudinal and transverse relaxation time constants (T1 and T2, respectively). Also acquired are diffusion-tensor MRI data, in which water diffusivity is measured and used to infer pathological processes such as edema. Quantitative magnetization transfer imaging is used to characterize the relative tissue content of macromolecular and free water protons. Lastly, fat-water MRI methods are used to characterize fibro-adipose tissue replacement of muscle. In addition to describing the data acquisition and analysis procedures, this paper also discusses the potential problems associated with these methods, the analysis and interpretation of the data, MRI safety, and strategies for artifact reduction and protocol optimization.

Indexed as

Adipose TissueDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance ImagingMuscle, SkeletalMuscular Diseases

Identifiers

PMID28060254
PMCPMC5226425
OpenAlexW2564744541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.