Evidence map›Paper›PMID 28060184›Full record

ArticlePancreas2017

Are Clinical Guidelines for the Management of Intraductal Papillary Mucinous Neoplasms Followed?: A Single-Center Analysis.

Parissa Tabrizian, Yaniv Berger, Elisa Sefora Pierobon, Samantha Aycart, Pamela Argiriadi, Kezhen Fei, Gonzalo Carrasco-Avino, Daniel M Labow, Umut Sarpel

Abstract read
In one paragraph

Article in Pancreas, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Pancreatic cystic neoplasms: Adherence to management recommendations and associated endosonographic cyst characteristics.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Parissa TabrizianFrom the *Recanati-Miller Transplantation Institute; Departments of †Surgery, Division of Surgical Oncology, ‡Radiology, §Health Evidence and Policy, Center for Biostatistics, and ∥Pathology, Icahn School of Medicine at Mount Sinai, New York, NY.
Yaniv Berger
Elisa Sefora Pierobon
Samantha Aycart
Pamela Argiriadi
Kezhen Fei
Gonzalo Carrasco-Avino
Daniel M Labow
Umut Sarpel

Funding

THE TISCH CANCER INSTITUTE - CANCER CENTER SUPPORT GRANTP30CA196521 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Deanna L Benson · 2015 to 2026
$35.4M
NCI NIH HHS P30 CA196521
6 · The paper itself

Abstract

objectivesThis study aimed to determine how frequently guidelines for the management of intraductal papillary mucinous neoplasms (IPMNs) are followed and establish factors associated with failure.

methodsFour hundred forty-five patients with radiographic diagnosis of IPMN 1 cm or greater between January 1, 2003 and January 1, 2013 were included. We defined failure of guideline adherence if the following occurred: (a) failure of acknowledgment of IPMN, (b) failure to undergo endoscopic ultrasound, (c) failure to undergo resection, or (d) failure to undergo at least 1 surveillance image within 2 years after diagnosis.

resultsFailure of guideline adherence was observed in 58% of patients and evident across all the respective criteria (A: 38%, B: 25%, C: 29%, D: 33%). Age older than 68 years (P < 0.01), American Society of Anesthesiologists score of 3 or higher (P < 0.0001), benign findings on imaging (P < 0.0001), and major comorbid conditions (P < 0.01) were factors associated with higher rate of failure to compliance. On multivariate logistic regression, American Society of Anesthesiologists score of 3 or higher and benign features were associated with 4.0 times (95% confidence interval, 2.02-8.06) and 2.6 times (95% confidence interval, 1.60-4.07) higher odds of failure to compliance with guidelines, respectively.

conclusionsCompliance with clinical guidelines for the management of IPMN is poor. Socioeconomic factors do not seem to create a disparity to care. However, many patients with IPMN have other medical diagnoses that take priority over IPMN surveillance and treatment.

Indexed as

Practice Guidelines as TopicAdenocarcinoma, MucinousAdenocarcinoma, PapillaryAgedAged, 80 and overCarcinoma, Pancreatic DuctalFemaleGuideline AdherenceHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPancreatic Neoplasms

Identifiers

PMID28060184
PMCPMC5990256

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.