Evidence map›Paper›PMID 28059704›Full record

ArticleeLife2017

Cooperative and acute inhibition by multiple C-terminal motifs of L-type Ca

Nan Liu, Yaxiong Yang, Lin Ge, Min Liu, Henry M Colecraft, Xiaodong Liu

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. C-Terminus of CaCells · 2026
    Article
  2. Article
  3. L-Type Voltage-Gated CaBiochemistry · 2025
    Article
  4. Role of the CaChannels (Austin, Tex.) · 2024
    Article
  5. Article
  6. Opto-chemogenetic inhibition of L-type CaCell reports methods · 2024
    Article
  7. Regulation of Cardiac Cav1.2 Channels by Calmodulin.International journal of molecular sciences · 2023
    Review
  8. Chronic CaeLife · 2022
    Article
  9. Cytosolic peptides encoding CaCommunications biology · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. The molecular basis of the inhibition of CaThe Journal of biological chemistry
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Nan LiuX-Lab for Transmembrane Signaling Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.ORCID 0000-0002-9606-4732
Yaxiong YangX-Lab for Transmembrane Signaling Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Lin GeX-Lab for Transmembrane Signaling Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Min LiuX-Lab for Transmembrane Signaling Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Henry M ColecraftDepartment of Physiology and Cellular Biophysics, Columbia University, New York, United States.
Xiaodong LiuX-Lab for Transmembrane Signaling Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.ORCID 0000-0002-3171-9611
Tsinghua University · CNChinese Institute for Brain Research · CNColumbia University · US

Funding

Molecular Determinants of L-type Calcium Channel GatingR01HL069911 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI COLECRAFT, HENRY M. · 2002 to 2011
$3.3M
Small G-protein Regulation of Calcium ChannelsR01GM107585 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COLECRAFT, HENRY M. · 2014 to 2017
$1.2M
NHLBI NIH HHS R01 HL069911NIGMS NIH HHS R01 GM107585
6 · The paper itself

Abstract

Inhibitions and antagonists of L-type Ca

Indexed as

CalciumCalcium Channel BlockersCalcium Channels, L-TypeHEK293 CellsHumansCalciumCalcium Channel BlockersCalcium Channels, L-TypebiophysicsCa2+ channel inhibitionCa2+ dependent inactivationcalmodulindistal carboxyl terminusL-type Ca2+ channelsneurosciencenonestructural biology

Identifiers

PMID28059704
PMCPMC5279948
OpenAlexW2571335787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.