Evidence map›Paper›PMID 28059612›Full record

ReviewGut microbes2017

Fecal microbial transplantation as a therapeutic option in patients colonized with antibiotic resistant organisms.

Michael Laffin, Braden Millan, Karen L Madsen

Abstract readReview
In one paragraph

Review in Gut microbes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Rational Design of Live Biotherapeutic Products for the Prevention ofbioRxiv : the preprint server for biology · 2024
    Article
  5. Cost-effectiveness of Fecal Microbiota Transplantation for First Recurrent Clostridioides difficile Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Antimicrobial Resistance Gene Acquisition and Depletion Following Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael Laffina Department of Medicine, CEGIIR: Center of Excellence for Gastrointestinal Inflammation and Immunity Research , University of Alberta , Edmonton , Alberta.
Braden Millanb Cumming School of Medicine , University of Calgary , Calgary , Alberta.
Karen L Madsena Department of Medicine, CEGIIR: Center of Excellence for Gastrointestinal Inflammation and Immunity Research , University of Alberta , Edmonton , Alberta.

Funding

CIHR
6 · The paper itself

Abstract

Despite increasing interest in fecal microbiota transplantation (FMT), its full therapeutic potential has yet to be determined. Since its increase in popularity, FMT has been shown to be highly effective in the treatment of both Clostridium difficile infection (CDI) and its recurrent form. Interest in FMT now expands well beyond the treatment of CDI to other processes with known associations to the microbiota such as antibiotic resistant infections, inflammatory bowel disease (IBD), hepatic encephalopathy, neuropsychiatric disorders, and metabolic disease. The rampant use and misuse of antibiotics in both medicine and agriculture has resulted in an increase in antibiotic resistant organisms which pose a significant risk to human health. The purpose of this commentary is to address the general issue of antibiotic resistance in the human microbiota and the restorative potential of FMT in this area.

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsClostridium InfectionsFecal Microbiota TransplantationFecesGastrointestinal MicrobiomeHepatic EncephalopathyHumansInflammatory Bowel DiseasesMental DisordersMetabolic DiseasesRisk FactorsAnti-Bacterial Agentsantibiotic resistanceantibioticsClostridium difficileFecal Microbiota TransplantationIntestinal microbiomeresistome

Identifiers

PMID28059612
PMCPMC5479404

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.