Evidence map›Paper›PMID 28059466›Full record

ArticleObesity (Silver Spring, Md.)2017

Validation of clinic weights from electronic health records against standardized weight measurements in weight loss trials.

Lan Xiao, Nan Lv, Lisa G Rosas, David Au, Jun Ma

Abstract readValidation Study
In one paragraph

Article in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lan XiaoResearch Institute, Palo Alto Medical Foundation, Palo Alto, California, USA.
Nan LvResearch Institute, Palo Alto Medical Foundation, Palo Alto, California, USA.
Lisa G RosasResearch Institute, Palo Alto Medical Foundation, Palo Alto, California, USA.
David AuDivision of Pulmonary and Critical Care Medicine, VA Puget Sound Health Care System, HSR&D, University of Washington, Seattle, Washington, USA.
Jun MaResearch Institute, Palo Alto Medical Foundation, Palo Alto, California, USA.

Funding

Can diet- & exercise-induced weight loss improve asthma control in obese adults?R01HL094466 · NHLBI · PALO ALTO MEDICAL FOUNDATION RES INST · PI MA, JUN · 2009 to 2013
$4.0M
A Pilot of Customized Continuous Care Management of Obesity in Pre-DiabeticsR34DK080878 · NIDDK · PALO ALTO MEDICAL FOUNDATION RES INST · PI MA, JUN · 2009 to 2010
$489k
NHLBI NIH HHS R01 HL094466NIDDK NIH HHS R34 DK080878
6 · The paper itself

Abstract

objectiveTo validate clinic weights in electronic health records against researcher-measured weights for outcome assessment in weight loss trials.

methodsClinic and researcher-measured weights from a published trial (BE WELL) were compared using Lin's concordance correlation coefficient, Bland and Altman's limits of agreement, and polynomial regression model. Changes in clinic and researcher-measured weights in BE WELL and another trial, E-LITE, were analyzed using growth curve modeling.

resultsAmong BE WELL (n = 330) and E-LITE (n = 241) participants, 96% and 90% had clinic weights (mean [SD] of 5.8 [6.1] and 3.7 [3.9] records) over 12 and 15 months of follow-up, respectively. The concordance correlation coefficient was 0.99, and limits of agreement plots showed no pattern between or within treatment groups, suggesting overall good agreement between researcher-measured and nearest-in-time clinic weights up to 3 months. The 95% confidence intervals for predicted percent differences fell within ±3% for clinic weights within 3 months of the researcher-measured weights. Furthermore, the growth curve slopes for clinic and researcher-measured weights by treatment group did not differ significantly, suggesting similar inferences about treatment effects over time, in both trials.

conclusionsCompared with researcher-measured weights, close-in-time clinic weights showed high agreement and inference validity. Clinic weights could be a valid pragmatic outcome measure in weight loss studies.

Indexed as

Electronic Health RecordsAdultFemaleHumansMaleMiddle AgedObesityResearch DesignWeight Loss

Identifiers

PMID28059466
PMCPMC5269438

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.