Evidence map›Paper›PMID 28059104›Full record

ArticleScientific reports2017

Synthesis and insecticidal activity of acridone derivatives to Aedes aegypti and Culex quinquefasciatus larvae and non-target aquatic species.

Selvaraj Mohana Roopan, Annadurai Bharathi, Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu, G Madhumitha

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Synthetic Strategies for the Development of Novel Heterocycles as Larvicides TargetingMedicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Selvaraj Mohana RoopanChemistry of Heterocycles &Natural Product Research Laboratory, Department of Chemistry, School of Advanced Sciences, VIT University, Vellore-632014, Tamil Nadu, India.
Annadurai BharathiChemistry of Heterocycles &Natural Product Research Laboratory, Department of Chemistry, School of Advanced Sciences, VIT University, Vellore-632014, Tamil Nadu, India.
Naif Abdullah Al-DhabiDepartment of Botany and Microbiology, Addiriyah Chair for Environmental Studies, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia.
Mariadhas Valan ArasuDepartment of Botany and Microbiology, Addiriyah Chair for Environmental Studies, College of Science, King Saud University, P. O. Box 2455, Riyadh, 11451, Saudi Arabia.
G MadhumithaChemistry of Heterocycles &Natural Product Research Laboratory, Department of Chemistry, School of Advanced Sciences, VIT University, Vellore-632014, Tamil Nadu, India.
Vellore Institute of Technology University · INKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A serious Mosquito borne yellow fever is one of the grave diseases which affect the major population. Since there is no specific treatment for yellow fever, there is a necessity to develop an effective agent. The series of acridinone analogues 3 to 5 were synthesized with help of non-conventional microwave heating and confirmed by respective spectral characterization. 5c and 3b showed highest activity to kill 90% of larvae against A. aegypti and C. quinquefasciatus, respectively. Also the active products were treated to check the mortality of non-target aquatic species. Through the reports of the larvicidal bioassay, compounds 3b against C. quinquefasciatus whereas 5c against A. aegypti were found to be more active. By keeping this as a platform, further extension of the work can be done to find out a valuable drug for controlling disease vectors.

Indexed as

AedesCulexAcetic AcidAcridonesAnimalsAquatic OrganismsHot TemperatureHydrazinesInsecticidesLarvaMetal NanoparticlesMicrowavesMosquito ControlMosquito VectorsPlant ExtractsPlant LeavesAcetic AcidacridoneAcridoneshydrazineHydrazinesInsecticidesPlant Extracts

Identifiers

PMID28059104
PMCPMC5216327
OpenAlexW2570773871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.