ArticleModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc2017
Biological relevance of human papillomaviruses in vulvar cancer.
Article in Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06007625 (Vulvar Cancer Individualized Scoring System), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Vulvar Cancer Individualized Scoring System
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
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- Hypothesis: HPV E6 and COVID spike proteins cooperate in targeting tumor suppression by p53.Oncotarget · 2026Article
- TP53 codon 47 and 72 polymorphisms show no association with HPV in Zimbabwean women living with HIV and histologically confirmed cervical and vulvar disease.Frontiers in reproductive health · 2026Article
- DNA methylation and copy number alterations in the progression of HPV-associated high-grade vulvar intraepithelial lesion.International journal of cancer · 2025Article
- Association of human papillomavirus 16 and 18 with ovarian cancer risk: Insights from a meta‑analysis.Oncology letters · 2024Article
- Gut and oral microbiota in gynecological cancers: interaction, mechanism, and therapeutic value.NPJ biofilms and microbiomes · 2024Review
- Time trends in human papillomavirus prevalence and genotype distribution in vulvar carcinoma in Norway.Acta obstetricia et gynecologica Scandinavica · 2024Article
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- Cancer incidence and mortality in 23 000 patients with type 1 diabetes in the UK: Long-term follow-up.International journal of cancer · 2023Article
- Human Papilloma Virus: An Unraveled Enigma of Universal Burden of Malignancies.Pathogens (Basel, Switzerland) · 2023Review
- Trends in HPV- and non-HPV-associated vulvar cancer incidence, United States, 2001-2017.Preventive medicine · 2022Article
- Essentiality of Trace Elements in Pregnancy, Fertility, and Gynecologic Cancers-A State-of-the-Art Review.Nutrients · 2021Review
- Viral Venereal Diseases of the Skin.American journal of clinical dermatology · 2021Review
- Human Papilloma Virus Vaccination.Viruses · 2021Review
- Article
- Vulvar intraepithelial neoplasia: Incidence and long-term risk of vulvar squamous cell carcinoma.International journal of cancer · 2021Article
- Insertional oncogenesis by HPV70 revealed by multiple genomic analyses in a clinically HPV-negative cervical cancer.Genes, chromosomes & cancer · 2020Article
- Role of human papillomavirus infection in the etiology of vulvar cancer in Italian women.Infectious agents and cancer · 2020Article
- Prognostic implications of genotyping and p16 immunostaining in HPV-positive tumors of the uterine cervix.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020Article
- Decorin Expression in Human Vulva Carcinoma: Oncosuppressive Effect of Decorin cDNA Transduction on Carcinoma Cells.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The carcinogenic role of high-risk human papillomavirus (HR-HPV) types in the increasing subset of vulvar intraepithelial neoplasia and vulvar cancer in young women has been established. However, the actual number of vulvar cancer cases attributed to HPV is still imprecisely defined. In an attempt to provide a more precise definition of HPV-driven vulvar cancer, we performed HPV-type-specific E6*I mRNA analyses available for 20 HR-/possible HR (pHR)-HPV types, on tissue samples from 447 cases of vulvar cancer. HPV DNA genotyping was performed using SPF10-LiPA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.