Evidence map›Paper›PMID 28058674›Full record

ArticleEJNMMI physics2017

Quantitative myocardial blood flow imaging with integrated time-of-flight PET-MR.

Tanja Kero, Jonny Nordström, Hendrik J Harms, Jens Sörensen, Håkan Ahlström, Mark Lubberink

Abstract read
In one paragraph

Article in EJNMMI physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Influence of image reconstruction on quantitative cardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  2. Diagnosis of left ventricular hypertrophy using non-ECG-gatedJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  3. Assessment of a digital and an analog PET/CT system for accurate myocardial perfusion imaging with a flow phantom.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  4. Quantitative myocardial perfusion response to adenosine and regadenoson in patients with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  5. Evaluation of quantitative CMR perfusion imaging by comparison with simultaneousJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  6. Review
  7. Renal statistical map for positron emission tomography with [O-15] water.American journal of nuclear medicine and molecular imaging · 2019
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tanja KeroNuclear Medicine & PET, Uppsala University, Uppsala, Sweden. tanja.kero@radiol.uu.se.
Jonny NordströmNuclear Medicine & PET, Uppsala University, Uppsala, Sweden.
Hendrik J HarmsDepartment of Nuclear Medicine and PET, Århus University Hospitals, Århus, Denmark.
Jens SörensenNuclear Medicine & PET, Uppsala University, Uppsala, Sweden.
Håkan AhlströmRadiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Mark LubberinkNuclear Medicine & PET, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of integrated PET-MR offers new opportunities for comprehensive assessment of cardiac morphology and function. However, little is known on the quantitative accuracy of cardiac PET imaging with integrated time-of-flight PET-MR. The aim of the present work was to validate the GE Signa PET-MR scanner for quantitative cardiac PET perfusion imaging. Eleven patients (nine male; mean age 59 years; range 46-74 years) with known or suspected coronary artery disease underwent

resultsStress MBF data from one patient was excluded due to movement during the PET-CT scanning. Mean MBF values at rest and stress were (0.92 ± 0.12) and (2.74 ± 1.37) mL/g/min for PET-CT and (0.90 ± 0.23) and (2.65 ± 1.15) mL/g/min for PET-MR (p = 0.33 and p = 0.74). ICC between PET-CT-based and PET-MR-based regional MBF was 0.98. Image quality was improved with PET-MR as compared to PET-CT. ICC between PET-MR-based regional MBF with and without TOF and using different filter and reconstruction settings was 1.00.

conclusionsPET-MR-based MBF values correlated well with PET-CT-based MBF values and the parametric PET-MR images were excellent. TOF and reconstruction settings had little impact on MBF values.

Indexed as

15O-waterMyocardial blood flow (MBF)PET-MRQuantificationTime-of-flight (TOF)

Identifiers

PMID28058674
PMCPMC5216001

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.