Trial reportAnnals of surgical oncology2017
Percutaneous Peritoneal Lavage for the Rapid Staging of Gastric and Pancreatic Cancer.
Trial report in Annals of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Peritoneal cytology in pancreatic cancer: a comprehensive review on prognostic stratification and clinical decision-making.Cancer metastasis reviews · 2026Review
- Endoscopic Ultrasound-Lavage Technique for Pancreatic Cancer: An In Vivo Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Phase 1 trial of lavage cytology collected with endoscopic ultrasound-guided fine-needle aspiration for preoperative pancreatic cancer.Endoscopy international open · 2026Article
- Outcomes of Resected Cases of Pancreatic Ductal Adenocarcinoma Patients With Unexpected Postoperative Uncovering Noncurative Factors: A Multicenter Retrospective Study.Annals of gastroenterological surgery · 2026Article
- Safety and feasibility of percutaneous abdominal lavage cytology screening (PACS) prior to surgical resection for pancreatic cancer.Abdominal radiology (New York) · 2024Article
- Exosomal ROR1 in peritoneal fluid identifies peritoneal disseminated PDAC and is associated with poor survival.Frontiers in immunology · 2024Article
- Article
- The value of potassium, pH and D-dimer levels in early diagnosis of acute mesenteric ischemia: an experimental study on rats.Archives of medical science : AMS · 2021Article
- A decision analysis comparing three strategies for peritoneal lavage cytology testing in staging of gastric cancer in China.Cancer medicine · 2020Article
- Article
- Free cancer cells in gastric cancer - methods of detection, clinical and prognostic importance (meta-analysis).Contemporary oncology (Poznan, Poland) · 2020Review
- Optimizing outcomes for patients with gastric cancer peritoneal carcinomatosis.World journal of gastrointestinal oncology · 2018Article
- Applying Precision Medicine to Ovarian Cancer: Proof-of-Principle for a "Molecular Second Look".International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPositive peritoneal cytology is classified as M1 disease in gastric and pancreatic cancer. While peritoneal cytology is typically obtained by laparoscopic peritoneal lavage, this study sought to examine the feasibility and safety of performing this percutaneously, with monitored anesthesia care and in combination with other diagnostic procedures to condense and expedite the staging process.
methodsPatients with gastric or pancreatic cancer scheduled for laparoscopy with peritoneal lavage were prospectively enrolled to undergo intraoperative percutaneous peritoneal lavage prior to laparoscopic peritoneal lavage. Saline was infused through a percutaneously-inserted catheter and fluid was collected for peritoneal cytology. Three-quadrant washings collected during laparoscopy were also sent for peritoneal cytology. The primary outcome was to evaluate the sensitivity and specificity of percutaneous peritoneal lavage for detecting positive peritoneal cytology compared with the gold standard of laparoscopic peritoneal lavage, while the secondary outcome was to determine safety.
resultsPercutaneous peritoneal lavage was successfully performed in 70 of 76 patients (92%). Ten of 48 gastric cancer patients (21%) and three of 22 pancreatic cancer patients (14%) had positive percutaneous and laparoscopic peritoneal cytology. Two additional gastric cancer patients had positive laparoscopic peritoneal cytology only. Sensitivity and specificity of percutaneous peritoneal lavage compared with laparoscopic peritoneal lavage were 87% and 100%, respectively. No complications occurred with percutaneous peritoneal lavage.
conclusionsPercutaneous peritoneal lavage is a safe and effective minimally invasive alternative to laparoscopic peritoneal lavage for the diagnosis of metastatic gastric and pancreatic cancer. It is possible this can be utilized in an outpatient setting, such as during endoscopy, to allow for earlier diagnosis of M1 disease and decreased time to appropriate treatment.
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