ArticleNorthern clinics of Istanbul2015
Neutrophil/lymphocyte ratio in obese adolescents.
Article in Northern clinics of Istanbul, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Association between the neutrophil-to-lymphocyte ratio and obstructive sleep apnea: a meta-analysis.Scientific reports · 2020Pooled it
- Review
- Body mass index mediates the association between neutrophil-to-lymphocyte ratio and impaired fasting glucose: evidence from a five-year follow-up study.Scientific reports · 2026Article
- Relationship Between Nutritional Status and Systemic Immune-Inflammation Indices Across BMI Categories.Nutrients · 2025Article
- Association between neutrophil/ high-density lipoprotein cholesterol ratio and BMI in three Argentinean Indigenous communities.Biochemistry and biophysics reports · 2025Article
- Insights into the clinical impact of complete blood cell inflammatory markers on body composition variations and fatty liver grading in Iranian adults undergoing bariatric surgery: a retrospective longitudinal study.Annals of medicine and surgery (2012) · 2024Article
- Endobiogenic Biology of Function Indices in a Cohort of Kidney Transplant Recipients.Medicina (Kaunas, Lithuania) · 2024Article
- Complete Blood Count-Derived Inflammation Indexes Are Useful in Predicting Metabolic Syndrome in Children and Adolescents with Severe Obesity.Journal of clinical medicine · 2024Article
- Relationship between inflammatory biomarkers and insulin resistance in excess-weight Latin children.Clinical and experimental pediatrics · 2024Article
- The neutrophil to lymphocyte ratio (NLR) positively correlates with the presence and severity of metabolic syndrome in obese adults, but not in obese children/adolescents.BMC endocrine disorders · 2023Article
- Establishment and evaluation of a risk-prediction model for hypertension in elderly patients with NAFLD from a health management perspective.Scientific reports · 2022Article
- Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios of overweight children and adolescents.Revista da Associacao Medica Brasileira (1992) · 2022Article
- Neutrophils Actively Contribute to Obesity-Associated Inflammation and Pathological Complications.Cells · 2022Review
- Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2.Cell discovery · 2021Article
- The Peculiar Trialogue between Pediatric Obesity, Systemic Inflammatory Status, and Immunity.Biology · 2021Review
- Association between Copper-Zinc Ratio in Hair and Neutrophil-Lymphocyte Ratio within the Context of a Normal White Blood Cell Count among Overweight or Obese Korean Individuals: A Pilot Study.Korean journal of family medicine · 2021Article
- Inflammation-Related Markers and Thyroid Function Measures in Pediatric Patients: Is the Grade of Obesity Relevant?Diagnostics (Basel, Switzerland) · 2021Article
- Role of neutrophils in ischemic heart failure.Pharmacology & therapeutics · 2020Review
- Early Inflammatory Status Related to Pediatric Obesity.Frontiers in pediatrics · 2019Article
- Neutrophil-to-lymphocyte ratio, obesity, and breast cancer risk in Chinese population.Medicine · 2018Observational
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveObesity is a growing health problem in most of the developed countries. It is associated with many chronic diseases, affecting particularly endocrine and cardiovascular systems. Inflammation plays a key role in pathophysiology of obesity. In this study, we aimed to investigate the inflammation status in obese children using neutrophil/lymphocyte ratio.
methodsIn this study 130 obese and 57 healthy children were assessed retrospectively. According to Centers for Disease Control 2000 (CDC) BMI percentiles for childhood and adulthood, 85-95 percentile was considered as overweight and >95 percentile as obese.
resultsLymphocyte/neutrophil ratios in the obese group were significantly higher compared to those in healthy controls (p=0.03 and p=0.045, respectively). Neutrophil/lymphocyte ratio and CRP level in the obese group were significantly higher compared to those in healthy controls (p=0.02 and p=0.00, respectively). Thrombocyte/lymphocyte ratios were not significantly different between two groups (p=0.156).
conclusionIt is possible that childhood obesity which has been increasingly prevalent recently triggers the pathogenesis of atherosclerosis during the early years of life. Increased neutrophil/lymphocyte ratio might be associated with the severity of inflammation which plays a role in the early stages of atherosclerosis. Therefore, taking childhood obesity under control using diet and other treatment methods will prevent mortality and morbidity in the elderly.
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