Evidence map›Paper›PMID 28058255›Full record

ArticleBioMed research international2016

Early Administration of Glutamine Protects Cardiomyocytes from Post-Cardiac Arrest Acidosis.

Yan-Ren Lin, Chao-Jui Li, Shih-Han Syu, Cheng-Hao Wen, Waradee Buddhakosai, Han-Ping Wu, Cheng Hsu Chen, Huai-En Lu, Wen-Liang Chen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Glutamine amelioratesThe journal of venomous animals and toxins including tropical diseases · 2023
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Yan-Ren LinDepartment of Emergency Medicine, Changhua Christian Hospital, Changhua, Taiwan; School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.ORCID 0000-0002-9015-2678
Chao-Jui LiDepartment of Emergency Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan; Department of Public Health, College of Health Science, Kaohsiung Medical University, Kaohsiung, Taiwan.ORCID 0000-0002-7777-2215
Shih-Han SyuBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan.
Cheng-Hao WenBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan.
Waradee BuddhakosaiDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan; Interdisciplinary Graduate Program in Genetic Engineering, Graduate School, Kasetsart University, Bangkhen Campus, Bangkok, Thailand.
Han-Ping WuDivision of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, Kweishan, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0002-0069-4183
Cheng Hsu ChenDepartment of Emergency Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Huai-En LuBioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan.ORCID 0000-0003-0875-9321
Wen-Liang ChenDepartment of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan.ORCID 0000-0003-4308-3128
Food Industry Research and Development Institute · TWKaohsiung Medical University · TWNational Yang Ming Chiao Tung University · TWChang Gung University · TWChanghua Christian Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postcardiac arrest acidosis can decrease survival. Effective medications without adverse side effects are still not well characterized. We aimed to analyze whether early administration of glutamine could improve survival and protect cardiomyocytes from postcardiac arrest acidosis using animal and cell models. Forty Wistar rats with postcardiac arrest acidosis (blood pH < 7.2) were included. They were divided into study (500 mg/kg L-alanyl-L-glutamine,

Indexed as

AcidosisAnimalsCells, CulturedDisease Models, AnimalGlutamineHeart ArrestHumansHydrogen-Ion ConcentrationInduced Pluripotent Stem CellsMyocytes, CardiacRatsRats, WistarGlutamine

Identifiers

PMID28058255
PMCPMC5183754
OpenAlexW2567275035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.