Evidence map›Paper›PMID 28058227›Full record

ArticleWorld journal of transplantation2016

Magnetic resonance imaging of the transplanted pediatric heart as a potential predictor of rejection.

Steven C Greenway, Frederic Dallaire, Paul F Kantor, Anne I Dipchand, Rajiv R Chaturvedi, Monali Warade, Eugenie Riesenkampff, Shi-Joon Yoo, Lars Grosse-Wortmann

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cardiac magnetic resonance assessment of acute rejection and cardiac allograft vasculopathy in pediatric heart transplant.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  5. Late-gadolinium enhancement is common in older pediatric heart transplant recipients and is associated with lower ejection fraction.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  6. Article
  7. Native T1 mapping detects both acute clinical rejection and graft dysfunction in pediatric heart transplant patients.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Steven C GreenwaySteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Frederic DallaireSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Paul F KantorSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Anne I DipchandSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Rajiv R ChaturvediSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Monali WaradeSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Eugenie RiesenkampffSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Shi-Joon YooSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
Lars Grosse-WortmannSteven C Greenway, Department of Paediatrics, University of Calgary, Calgary, AB T2N 1N4, Canada.
University of Calgary · CACentre Hospitalier Universitaire de Sherbrooke · CAHospital for Sick Children · CASickKids Foundation · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate cardiac magnetic resonance imaging (CMR) as a non-invasive tool to detect acute cellular rejection (ACR) in children after heart transplant (HT).

methodsThirty pediatric HT recipients underwent CMR at the time of surveillance endomyocardial biopsy (EMB) and results were compared to 14 non-transplant controls. Biventricular volumes, ejection fractions (EFs), T2-weighted signal intensities, native T1 times, extracellular volumes (ECVs) and presence of late gadolinium enhancement (LGE) were compared between patients and controls and between patients with International Society of Heart and Lung Transplantation (ISHLT) grade ≥ 2R rejection and those with grade 0/1R. Heart rate (HR) and brain natriuretic peptide (BNP) were assessed as potential biomarkers.

resultsSignificant ACR (ISHLT grade ≥ 2R) was an infrequent event in our population (5/30, 17%). Ventricular volumes, EFs, LGE prevalence, ECVs, native T1 times, T2 signal intensity ratios, HR and BNP were not associated with the presence of ≥ 2R ACR.

conclusionIn this pilot study CMR did not reliably identify ACR-related changes in pediatric HT patients.

Indexed as

HeartMagnetic resonance imagingPediatricRejectionTransplantation

Identifiers

PMID28058227
PMCPMC5175235
OpenAlexW2561045132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.