Evidence map›Paper›PMID 28058164›Full record

ArticleTurkish journal of ophthalmology2016

The Efficacy of Intravitreal Bevacizumab in Vitreous Hemorrhage of Diabetic Subjects.

Cengiz Alagöz, Yusuf Yıldırım, Murat Kocamaz, Ökkeş Baz, Uğur Çiçek, Burcu Çelik, Halil İbrahim Demirkale, Ahmet Taylan Yazıcı, Muhittin Taşkapılı

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Intravitreal ziv-aflibercept in diabetic vitreous hemorrhage.International journal of retina and vitreous · 2020
    Review
  5. Intraocular Hemorrhage due to use of Sildenafil in a Patient with Diabetes.Medical hypothesis, discovery & innovation ophthalmology journal · 2018
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cengiz AlagözBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Yusuf YıldırımBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Murat KocamazBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Ökkeş BazBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Uğur ÇiçekBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Burcu ÇelikBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Halil İbrahim DemirkaleBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Ahmet Taylan YazıcıBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Muhittin TaşkapılıBeyoğlu Eye Training and Research Hospital, İstanbul, Turkey.
Istanbul Eye Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the efficacy of intravitreal bevacizumab (IVB) in the resolution of vitreous hemorrhage (VH) secondary to proliferative diabetic retinopathy (PDR). MATERIALS AND

methodsSeventy eyes of 70 patients (43 male, mean age 55.6±12.2 years) diagnosed with VH secondary to PDR were evaluated retrospectively. Demographic characteristics of the patients, baseline and final clinical results, and the interventions the patients were subject to were recorded. The patients who received IVB injections (group 1, n=29) were compared to those who did not receive injections (group 2, n=41) in terms of VH clearance time and surgery rates.

resultsThe mean follow-up time was 14.5±6.1 months in group 1 and 18.4±9.6 months in group 2 (p=0.185). The mean visual acuity was similar between the groups at baseline and at the last visit (for all p>0.05). Panretinal photocoagulation could be applied in 86% of subjects in group 1 and in 58% in group 2 2 within the first month (p=0.016). VH clearance time was not different between the groups (2.3±2.1 months in group 1 and 3.4±2.6 months in group 2, p=0.146). The number of subjects requiring surgery was 7 (24%) in group 1 and 20 (48.8%) in group 2 (p=0.048).

conclusionIVB was found effective in cases with VH secondary to PDR in terms of reducing the need for surgery and increasing the rate of subjects to whom panretinal photocoagulation could be applied in the early period, although there was no impact on final visual acuity.

Indexed as

intravitreal bevacizumabProliferative diabetic retinopathyvitreous hemorrhage

Identifiers

PMID28058164
PMCPMC5200834
OpenAlexW2537373068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.