Evidence map›Paper›PMID 28058085›Full record

ArticleBiomicrofluidics2016

Microfluidic cytometers with integrated on-chip optical systems for red blood cell and platelet counting.

Yingying Zhao, Qin Li, Xiaoming Hu, Yuhwa Lo

Abstract read
In one paragraph

Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  5. Review
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  8. Article
  9. A Soft Sensor for Bleeding Detection in Colonoscopies.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Cell Cytometry: Review and Perspective on Biotechnological Advances.Frontiers in bioengineering and biotechnology · 2019
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingying ZhaoSchool of Life Science, Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, Beijing Institute of Technology , Beijing 100081, China.
Qin LiSchool of Life Science, Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, Beijing Institute of Technology , Beijing 100081, China.
Xiaoming HuSchool of Life Science, Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, Beijing Institute of Technology , Beijing 100081, China.
Yuhwa LoDepartment of Electrical and Computer Engineering, University of California San Diego , California 92093-0407, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A microfluidic cytometer with integrated on-chip optical systems was designed for red blood cell (RBC) and platelet (PLT) counting. The design, fabrication, and characterization of the microfluidic cytometer with on-chip optical signal detection were described. With process using only a single mask, the device that integrates optical fibers and on-chip microlens with microfluidic channels on a polydimethylsiloxane layer by standard soft photolithography. This compact structure increased the sensitivity of the device and eliminated time-consuming free-space optical alignments. The microfluidic cytometer was used to count red blood cells and platelets. Forward scatter and extinction were collected simultaneously for each cell. Experimental results indicated that the microfluidic cytometer exhibited comparable performance with a conventional cytometer and demonstrated superior capacity to detect on-chip optical signals in a highly compact, simple, truly portable, and low-cost format that is well suitable for point-of-care clinical diagnostics.

Identifiers

PMID28058085
PMCPMC5188361

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.