ArticleProceedings of the National Academy of Sciences of the United States of America2017
Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Double-blind, Randomised, Placebo-controlled Parallel Study to Investigate the Influence of Dietary Nitrate on Skin Inflammation in Healthy Volunteers
Investigation of Dietary Nitrate Optimisation by Hyperuricaemia Stratification in Heart Failure
Who cites it
32 citing papers in PubMed, 78 citations in OpenAlex.
- Effect of Beetroot Extract Supplementation on Serum Fatty Acid Profiles and Oxidative Stress Markers in Chronic Coronary Artery Disease Patients: A Secondary Analysis of a Randomized Controlled Trial.BioMed research international · 2025Trial
- Trial
- Inorganic nitrate supplementation enhances functional capacity and lower-limb microvascular reactivity in patients with peripheral artery disease.Nitric oxide : biology and chemistry · 2018Trial
- Trial
- Diaryl-Aminoindazole with Extensive In Vitro Mycobactericidal Activity Dependent on Exposure to Reactive Nitrogen Species.ACS infectious diseases · 2026Article
- Retrospective cohort analysis of nitrite and nitrate levels in postmortem biological samples after suspected suicide, 2019-24.BMJ public health · 2026Article
- Sodium Nitrate Combined With Dental Pulp Stem Cells Alleviates Atherosclerosis Through Inhibiting Oxidative Stress.Stem cells international · 2026Article
- Dietary Nitrate Prevents Cardiac Dysfunction in HFrEF by Improving Hemodynamics, Ameliorating Remodeling, and Resolving Inflammation.Acta physiologica (Oxford, England) · 2025Article
- Relationship Between Periodontitis and Nitric Oxide in Patients Undergoing Maintenance Hemodialysis.Hemodialysis international. International Symposium on Home Hemodialysis · 2025Article
- Interplay between dietary nitrate metabolism and proton pump inhibitors: impact on nitric oxide pathways and health outcomes.Frontiers in nutrition · 2025Review
- Sodium nitrate regulates senescence accompanied by aortic atherosclerosis in ApoEFrontiers in pharmacology · 2025Article
- Potential Opportunities for Pharmacogenetic-Based Therapeutic Exploitation of Xanthine Dehydrogenase in Cardiovascular Disease.Antioxidants (Basel, Switzerland) · 2024Review
- The NITRATE-OCT study-inorganic nitrate reduces in-stent restenosis in patients with stable coronary artery disease: a double-blind, randomised controlled trial.EClinicalMedicine · 2024Article
- Exploring the wound healing potential of dietary nitrate in diabetic rat model.Frontiers in physiology · 2024Article
- Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke.Journal of neuroinflammation · 2023Article
- Long-term dietary nitrate supplementation slows the progression of established atherosclerosis in ApoEEuropean journal of nutrition · 2023Article
- Heart-targeted amelioration of sepsis-induced myocardial dysfunction by microenvironment responsive nitric oxide nanogenerators in situ.Journal of nanobiotechnology · 2022Article
- Homeostatic medicine: a strategy for exploring health and disease.Current medicine (Cham, Switzerland) · 2022Review
- Nitrate Metabolism and Ischemic Cerebrovascular Disease: A Narrative Review.Frontiers in neurology · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Reduced bioavailable nitric oxide (NO) plays a key role in the enhanced leukocyte recruitment reflective of systemic inflammation thought to precede and underlie atherosclerotic plaque formation and instability. Recent evidence demonstrates that inorganic nitrate (NO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.