Evidence map›Paper›PMID 28057819›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017

A new method to evaluate macaque health using exhaled breath: A case study of

Theodore R Mellors, Lionel Blanchet, JoAnne L Flynn, Jaime Tomko, Melanie O'Malley, Charles A Scanga, Philana L Lin, Jane E Hill

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Human Breathomics Database.Database : the journal of biological databases and curation · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Theodore R MellorsSchool of Engineering, Dartmouth College, Hanover, New Hampshire.
Lionel BlanchetSchool of Engineering, Dartmouth College, Hanover, New Hampshire.
JoAnne L FlynnDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
Jaime TomkoDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
Melanie O'MalleyDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
Charles A ScangaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; and.
Philana L LinDepartment of Pediatrics, Division of Infectious Disease, Children's Hospital of UPMC, Pittsburgh, Pennsylvania.
Jane E HillSchool of Engineering, Dartmouth College, Hanover, New Hampshire; jane.e.hill@dartmouth.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breath is hypothesized to contain clinically relevant information, useful for the diagnosis and monitoring of disease, as well as understanding underlying pathogenesis. Nonhuman primates, such as the cynomolgus macaque, serve as an important model for the study of human disease, including over 70 different human infections. In this feasibility study, exhaled breath was successfully collected in less than 5 min under Biosafety Level 3 conditions from five anesthetized, intubated cynomolgus and rhesus macaques, before and after lung infection with

Indexed as

AnimalsBiomarkersBreath TestsContainment of BiohazardsFeasibility StudiesGas Chromatography-Mass SpectrometryMacacaPilot ProjectsReproducibility of ResultsSensitivity and SpecificityTuberculosis, PulmonaryBiomarkersbreathGC×GC-TOFMSmacaquetuberculosis

Identifiers

PMID28057819
PMCPMC5401956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.