Evidence map›Paper›PMID 28057791›Full record

ReviewCirculation research2017

From Microscale Devices to 3D Printing: Advances in Fabrication of 3D Cardiovascular Tissues.

Anton V Borovjagin, Brenda M Ogle, Joel L Berry, Jianyi Zhang

Abstract readReview
In one paragraph

Review in Circulation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Review
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  4. Artificial blood vessels-clinical development of TEVG.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Review
  5. Article
  6. Review
  7. Application of human cardiac organoids in cardiovascular disease research.Frontiers in cell and developmental biology · 2025
    Review
  8. Article
  9. Review
  10. Materials today. Bio · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Progress in Bioengineering Strategies for Heart Regenerative Medicine.International journal of molecular sciences · 2022
    Review
  15. Article
  16. Reconstructing the heart using iPSCs: Engineering strategies and applications.Journal of molecular and cellular cardiology · 2021
    Review
  17. Article
  18. Recent advances in bioprinting technologies for engineering cardiac tissue.Materials science & engineering. C, Materials for biological applications · 2021
    Review
  19. Article
  20. Challenges and Possibilities of Cell-Based Tissue-Engineered Vascular Grafts.Cyborg and bionic systems (Washington, D.C.) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anton V BorovjaginFrom the Department of Biomedical Engineering, School of Medicine, School of Engineering, The University of Alabama at Birmingham (A.V.B., J.L.B., J.Z.); and Department of Biomedical Engineering, College of Science and Engineering, The University of Minnesota, Minneapolis (B.M.O.).
Brenda M OgleFrom the Department of Biomedical Engineering, School of Medicine, School of Engineering, The University of Alabama at Birmingham (A.V.B., J.L.B., J.Z.); and Department of Biomedical Engineering, College of Science and Engineering, The University of Minnesota, Minneapolis (B.M.O.).
Joel L BerryFrom the Department of Biomedical Engineering, School of Medicine, School of Engineering, The University of Alabama at Birmingham (A.V.B., J.L.B., J.Z.); and Department of Biomedical Engineering, College of Science and Engineering, The University of Minnesota, Minneapolis (B.M.O.).
Jianyi ZhangFrom the Department of Biomedical Engineering, School of Medicine, School of Engineering, The University of Alabama at Birmingham (A.V.B., J.L.B., J.Z.); and Department of Biomedical Engineering, College of Science and Engineering, The University of Minnesota, Minneapolis (B.M.O.). jayzhang@uab.edu.

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Integrated Cellular and Tissue Engineering for Ischemic Heart DiseaseU01HL134764 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BURSAC, NENAD, KAMP, TIMOTHY J. · 2016 to 2022
$7.7M
Supplement of HL131017: Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytesR01HL131017 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SERPOOSHAN, VAHID, ZHANG, JIANYI · 2016 to 2025
$5.8M
Endogenous and exogenous mechanisms that promote myocardial remuscularization in post infarction LV remodelingR01HL114120 · NHLBI · UNIVERSITY OF MINNESOTA · PI ZHANG, JIANYI · 2012 to 2021
$5.6M
Stem Cells For Myocardial Repair: A Large Bore Magnet StudyR01HL095077 · NHLBI · UNIVERSITY OF MINNESOTA · PI ZHANG, JIANYI · 2009 to 2017
$3.8M
NHLBI NIH HHS R01 HL095077NHLBI NIH HHS R01 HL114120NHLBI NIH HHS R01 HL131017NHLBI NIH HHS U01 HL134764NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Current strategies for engineering cardiovascular cells and tissues have yielded a variety of sophisticated tools for studying disease mechanisms, for development of drug therapies, and for fabrication of tissue equivalents that may have application in future clinical use. These efforts are motivated by the need to extend traditional 2-dimensional (2D) cell culture systems into 3D to more accurately replicate in vivo cell and tissue function of cardiovascular structures. Developments in microscale devices and bioprinted 3D tissues are beginning to supplant traditional 2D cell cultures and preclinical animal studies that have historically been the standard for drug and tissue development. These new approaches lend themselves to patient-specific diagnostics, therapeutics, and tissue regeneration. The emergence of these technologies also carries technical challenges to be met before traditional cell culture and animal testing become obsolete. Successful development and validation of 3D human tissue constructs will provide powerful new paradigms for more cost effective and timely translation of cardiovascular tissue equivalents.

Indexed as

Printing, Three-DimensionalTissue ScaffoldsAnimalsCardiovascular SystemCell Culture TechniquesHumansMyocytes, CardiacTissue Engineeringbiocompatible materialsheartprinting, three-dimensionalstem cellstissue engineering

Identifiers

PMID28057791
PMCPMC5224928

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.