Evidence map›Paper›PMID 28057609›Full record

ArticleJournal of medical Internet research2017

IntelliCare: An Eclectic, Skills-Based App Suite for the Treatment of Depression and Anxiety.

David C Mohr, Kathryn Noth Tomasino, Emily G Lattie, Hannah L Palac, Mary J Kwasny, Kenneth Weingardt, Chris J Karr, Susan M Kaiser, Rebecca C Rossom, Leland R Bardsley and 3 more

5 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Journal of medical Internet research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 148 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
148citing papers in PubMed, 7 pooled it
26.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02176226 nacompletednot on this map

Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM)

TypeinterventionalSponsorNorthwestern UniversityRan2015 to 2016Enrolled105ConditionsMajor Depressive Disorder, Anxiety DisordersArmsIntelliCare
NCT03552900 nacompletednot on this mapstarted 2018, after this paper: background citation

Evaluating the Use of a Mobile App to Reduce Symptoms of Depression and Anxiety for Students Seeking Care at Harvard University Health Services

TypeinterventionalSponsorHarvard UniversityRan2018 to 2018Enrolled50ConditionsDepression, AnxietyArms7cups Mobile App, Bliss
NCT04226742 nacompletednot on this mapstarted 2021, after this paper: background citation

Evaluation of the Crowd-Powered Web Platform for Accumulative Depression and Anxiety Plans and Treatment (ADAPT)

TypeinterventionalSponsorUniversity of California, IrvineRan2021 to 2022Enrolled107ConditionsDepression, AnxietyArmsADAPT Platform (Treatment), ADAPT Comparison (Control)
NCT04638231 nacompletednot on this mapstarted 2021, after this paper: background citation

Supportive Text Messaging Versus Supportive E-mail Messaging for Patients With Major Depressive Disorder - A Non-Inferiority Randomized Trial

TypeinterventionalSponsorUniversity of AlbertaRan2021 to 2023Enrolled66ConditionsMajor Depressive DisorderArmsSupportive messages
NCT05746767 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

SUPERA: Supporting Peer Interactions to Expand Access to Digital Cognitive Behavioral Therapy for Spanish-speaking Safety-Net Patients in Primary Care

TypeinterventionalSponsorUniversity of California, IrvineRan2024 to 2028Enrolled426ConditionsDepression, AnxietyArmsSupported dCBT, Unsupported dCBT
3 · Its place in the literature

Who cites it

148 citing papers in PubMed, 7 syntheses or guidelines pooled it, 329 citations in OpenAlex.

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88 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

David C MohrCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-3184-6338
Kathryn Noth TomasinoCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-4905-8807
Emily G LattieCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-3069-5996
Hannah L PalacCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0003-1314-3329
Mary J KwasnyDepartment of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0003-3287-1903
Kenneth WeingardtCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-9026-4995
Chris J KarrAudacious Software, Chicago, IL, United States.ORCID 0000-0003-1828-4497
Susan M KaiserCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-5749-2072
Rebecca C RossomHealthPartners Institute, Minneapolis, MN, United States.ORCID 0000-0002-9531-914X
Leland R BardsleyCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-7560-1666
Lauren CaccamoCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0003-2052-5843
Colleen Stiles-ShieldsCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-6759-8380
Stephen M SchuellerCenter for Behavioral Intervention Technologies (CBITs), Department of Preventive Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-1003-0399
Northwestern University · USHealthPartners · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Artificial Intelligence in a Mobile Intervention for Depression (AIM)R01MH100482 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MOHR, DAVID CURTIS · 2013 to 2017
$3.1M
Novel Methods for Evaluation and Implementation of Behavioral Intervention Technologies for DepressionR01MH109496 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHEUNG, KEN, MOHR, DAVID CURTIS · 2016 to 2019
$1.6M
Connecting Patients and Therapists Using a Tech-Based Treatment Support SystemK08MH102336 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHUELLER, STEPHEN · 2014 to 2017
$678k
NCATS NIH HHS UL1 TR001422NCI NIH HHS P30 CA060553NIMH NIH HHS K08 MH102336NIMH NIH HHS R01 MH100482NIMH NIH HHS R01 MH109496
6 · The paper itself

Abstract

backgroundDigital mental health tools have tended to use psychoeducational strategies based on treatment orientations developed and validated outside of digital health. These features do not map well to the brief but frequent ways that people use mobile phones and mobile phone apps today. To address these challenges, we developed a suite of apps for depression and anxiety called IntelliCare, each developed with a focused goal and interactional style. IntelliCare apps prioritize interactive skills training over education and are designed for frequent but short interactions.

objectiveThe overall objective of this study was to pilot a coach-assisted version of IntelliCare and evaluate its use and efficacy at reducing symptoms of depression and anxiety.

methodsParticipants, recruited through a health care system, Web-based and community advertising, and clinical research registries, were included in this single-arm trial if they had elevated symptoms of depression or anxiety. Participants had access to the 14 IntelliCare apps from Google Play and received 8 weeks of coaching on the use of IntelliCare. Coaching included an initial phone call plus 2 or more texts per week over the 8 weeks, with some participants receiving an additional brief phone call. Primary outcomes included the Patient Health Questionnaire-9 (PHQ-9) for depression and the Generalized Anxiety Disorder-7 (GAD-7) for anxiety. Participants were compensated up to US $90 for completing all assessments; compensation was not for app use or treatment engagement.

resultsOf the 99 participants who initiated treatment, 90.1% (90/99) completed 8 weeks. Participants showed substantial reductions in the PHQ-9 and GAD-7 (P<.001). Participants used the apps an average of 195.4 (SD 141) times over the 8 weeks. The average length of use was 1.1 (SD 2.1) minutes, and 95% of participants downloaded 5 or more of the IntelliCare apps.

conclusionsThis study supports the IntelliCare framework of providing a suite of skills-focused apps that can be used frequently and briefly to reduce symptoms of depression and anxiety. The IntelliCare system is elemental, allowing individual apps to be used or not used based on their effectiveness and utility, and it is eclectic, viewing treatment strategies as elements that can be applied as needed rather than adhering to a singular, overarching, theoretical model.

trial registrationClinicaltrials.gov NCT02176226; http://clinicaltrials.gov/ct2/show/NCT02176226 (Archived by WebCite at http://www.webcitation/6mQZuBGk1).

Indexed as

Cell PhoneMobile ApplicationsTelemedicineAdultAnxietyDepressionFemaleHumansMaleMiddle AgedanxietydepressioneHealthmHealthmobile health

Identifiers

PMID28057609
PMCPMC5247623
OpenAlexW2570496662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.