Evidence map›Paper›PMID 28057031›Full record

ArticleBreast cancer research : BCR2017

David Groheux, Antoine Martineau, Luis Teixeira, Marc Espié, Patricia de Cremoux, Philippe Bertheau, Pascal Merlet, Charles Lemarignier

Open access · goldAbstract read
In one paragraph

Article in Breast cancer research : BCR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Joint EANM-SNMMI guideline on the role of 2-[European journal of nuclear medicine and molecular imaging · 2024
    Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The use of 3'-deoxy-3'-Annals of nuclear medicine · 2019
    Trial
  6. Trial
  7. Article
  8. Relationship Between [European journal of breast health · 2025
    Article
  9. Article
  10. BaselineLa Radiologia medica · 2025
    Article
  11. Article
  12. A PET-Surrogate Signature for the Interrogation of the Metabolic Status of Breast Cancers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  13. Article
  14. Cancers · 2023
    Article
  15. Prognostic significance of pretreatmentBreast cancer research and treatment · 2023
    Article
  16. Article
  17. Article
  18. Frontiers in oncology · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

David GroheuxDepartment of Nuclear Medicine, Saint-Louis Hospital, Paris, France. dgroheux@yahoo.fr.ORCID 0000-0002-9541-9175
Antoine MartineauDepartment of Nuclear Medicine, Saint-Louis Hospital, Paris, France.
Luis TeixeiraUniversity Paris-Diderot, INSERM/CNRS UMR944/7212, Paris, France.
Marc EspiéUniversity Paris-Diderot, INSERM/CNRS UMR944/7212, Paris, France.
Patricia de CremouxUniversity Paris-Diderot, INSERM/CNRS UMR944/7212, Paris, France.
Philippe BertheauDepartment of Pathology, Saint-Louis Hospital, Paris, France.
Pascal MerletDepartment of Nuclear Medicine, Saint-Louis Hospital, Paris, France.
Charles LemarignierDepartment of Nuclear Medicine, Saint-Louis Hospital, Paris, France.
Centre National de la Recherche Scientifique · FRHôpital Saint-Louis · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study investigated the value of some clinicopathological parameters and 18 F-fluorodeoxyglucose-positron emission tomography/computed tomography (

methodsFDG-PET/CT indices and clinicopathological parameters were assessed before neoadjuvant chemotherapy (NAC). After completion of chemotherapy, all patients had breast surgery with axillary lymph node dissection, followed by radiation therapy and endocrine therapy for 5 years. EFS was estimated using the Kaplan-Meier method. A Cox proportional hazard regression model was used for multivariate analysis.

resultsOne hundred forty-three consecutive patients with stage II-III ER+/HER2- BC and without distant metastases at baseline PET were included. High standardized uptake values (SUVs), were associated with shorter EFS (HR = 3.51, P < 0.01 for SUV

conclusionsBaseline PET parameters measured before neoadjuvant treatment have prognostic values in ER+/HER2- locally advanced breast cancer patients. After multivariate analysis, metabolically active tumor volume remains significant while textural analysis of PET images is not of added value. Considering histopathological parameters, our study shows that patients with PR-negative or lobular invasive tumor have poorer prognosis than patients with PR-positive or ductal carcinoma, respectively.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyAdultAgedBreast NeoplasmsErb-b2 Receptor Tyrosine KinasesFemaleHumansImage Processing, Computer-AssistedImmunohistochemistryMiddle AgedNeoplasm GradingNeoplasm StagingPatient Outcome AssessmentPositron-Emission TomographyPrognosisErb-b2 Receptor Tyrosine KinasesFluorodeoxyglucose F18Receptors, Estrogen18FDG-PET/CTER+/HER2- breast cancerMetabolically active tumor volumePrognosisSUVTextural parameters

Identifiers

PMID28057031
PMCPMC5217422
OpenAlexW2569051210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.