Evidence map›Paper›PMID 28056812›Full record

ArticleBMC gastroenterology2017

Relationship of body weight with gastrointestinal motor and sensory function: studies in anorexia nervosa and obesity.

Sena Bluemel, Dieter Menne, Gabriella Milos, Oliver Goetze, Michael Fried, Werner Schwizer, Mark Fox, Andreas Steingoetter

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00946816 (The Effects of Dietary Intervention on Gastrointestinal Motility, Hormonal Feedback, Visceral Sensation and Satiety in Patients With Anorexia Nervosa and Obesity), which is not on this map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00946816 nacompletednot on this map

The Effects of Dietary Intervention on Gastrointestinal Motility, Hormonal Feedback, Visceral Sensation and Satiety in Patients With Anorexia Nervosa and Obesity

TypeinterventionalSponsorUniversity of ZurichRan2010 to 2012Enrolled60ConditionsAnorexia Nervosa, Obesity, Healthy ParticipantsArmsNutritional Intervention
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Disorders of the brain-gut interaction and eating disorders.World journal of gastroenterology · 2021
    Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Sensing the Self: The Role of the Insula and Interoception in Body Image.Current topics in behavioral neurosciences · 2025
    Review
  10. Are youPersonality neuroscience · 2024
    Review
  11. Observational
  12. Article
  13. Observational
  14. Effect of SitagliptinMaedica · 2022
    Article
  15. Article
  16. Review
  17. Article
  18. Evaluating disorders of gut-brain interaction in eating disorders.The International journal of eating disorders · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sena BluemelDivision of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Dieter MenneMenne Biomed Consulting, Tuebingen, Germany.
Gabriella MilosPsychiatric Department, University Hospital Zurich, Zurich, Switzerland.
Oliver GoetzeDivision of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Michael FriedDivision of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Werner SchwizerDivision of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Mark FoxDivision of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Andreas SteingoetterDivision of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland. steingoetter@biomed.ee.ethz.ch.
Swiss Integrative Center for Human Health · CHInstitute for Biomedical Engineering · CHUniversity Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether gastrointestinal motor and sensory function is primary cause or secondary effect of abnormal body weight is uncertain. Moreover, studies relating continuous postprandial sensations of satiation to measurable pathology are scarce. This work assessed postprandial gastrointestinal function and concurrent sensations of satiation across a wide range of body weight and after weight change.

methodsPatients with anorexia nervosa (AN) and obesity (OB) were investigated in reference to normal weight controls (HC). AN were additionally investigated longitudinally. Gastric emptying, antral contractions and oro-cecal transit after ingestion of a solid meal were investigated by MRI and

results24 AN (BMI 14.4 (11.9-16.0) kg/m

conclusionsA relationship between body weight and gastric emptying as well as self-reported feelings of satiation is present. AN have slower gastric emptying and heightened visceral perception compared to HC and OB. Longitudinal follow-up after weight rehabilitation in AN suggests these abnormalities are not a primary feature, but secondary to other factors that determine abnormal body weight.

trial registrationRegistered July 20, 2009 at ClinicalTrials.gov ( NCT00946816 ).

Indexed as

AdolescentAdultAnorexia NervosaBody WeightCase-Control StudiesDigestionEatingFemaleGastric EmptyingHumansMaleMiddle AgedObesityPostprandial PeriodSensationYoung AdultAnorexia NervosaGastric emptyingGastrointestinal transitObesityVisceral sensations

Identifiers

PMID28056812
PMCPMC5217542
OpenAlexW2568322288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.