Evidence map›Paper›PMID 28056549›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2017

PEGylated long-circulating liposomes deliver homoharringtonine to suppress multiple myeloma cancer stem cells.

Miao Li, Fangfang Shi, Xiong Fei, Songyan Wu, Di Wu, Meng Pan, Shouhua Luo, Ning Gu, Jun Dou

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Miao Li1 Department of Pathogenic Biology and Immunology, School of Medicine, Southeast University, Nanjing 210009, China.
Fangfang Shi1 Department of Pathogenic Biology and Immunology, School of Medicine, Southeast University, Nanjing 210009, China.
Xiong Fei2 School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, China Miao Li and Fangfang Shi contributed equally to the work.
Songyan Wu1 Department of Pathogenic Biology and Immunology, School of Medicine, Southeast University, Nanjing 210009, China.
Di Wu1 Department of Pathogenic Biology and Immunology, School of Medicine, Southeast University, Nanjing 210009, China.
Meng Pan1 Department of Pathogenic Biology and Immunology, School of Medicine, Southeast University, Nanjing 210009, China.
Shouhua Luo2 School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, China Miao Li and Fangfang Shi contributed equally to the work.
Ning Gu2 School of Biological Science & Medical Engineering, Southeast University, Nanjing 210096, China Miao Li and Fangfang Shi contributed equally to the work.
Jun Dou1 Department of Pathogenic Biology and Immunology, School of Medicine, Southeast University, Nanjing 210009, China.
Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this investigation was to evaluate the inhibiting effect of high proportion polyethyleneglycol of long-circulating homoharringtonine liposomes on RPMI8226 multiple myeloma cancer stem cells. The CD138

Indexed as

AnimalsAntineoplastic Agents, PhytogenicApoptosisCell Line, TumorCell ProliferationDisease Models, AnimalDrug CarriersHarringtoninesHomoharringtonineHumansLiposomesMiceMice, SCIDMultiple MyelomaNeoplastic Stem CellsTreatment OutcomeAntineoplastic Agents, PhytogenicDrug CarriersHarringtoninesHomoharringtonineLiposomescancer stem cellshomoharringtoninelong-circulating liposomesMultiple myelomapolyethyleneglycol

Identifiers

PMID28056549
PMCPMC5407585
OpenAlexW2568928303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.