Evidence map›Paper›PMID 28055298›Full record

ArticleEpigenetics2018

Vitamin D limits inflammation-linked microRNA expression in adipocytes in vitro and in vivo: A new mechanism for the regulation of inflammation by vitamin D.

Esma Karkeni, Lauriane Bonnet, Julie Marcotorchino, Franck Tourniaire, Julien Astier, Jianping Ye, Jean-François Landrier

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 128 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. 1α,25(OH)Nutrients · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Vitamin DFrontiers in immunology · 2026
    Review
  12. The Role of Vitamin D and Vitamin D Receptor in Sepsis.Current issues in molecular biology · 2025
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Esma Karkenia NORT , Aix-Marseille Université , INRA, INSERM, 13000 , Marseille , France.
Lauriane Bonneta NORT , Aix-Marseille Université , INRA, INSERM, 13000 , Marseille , France.
Julie Marcotorchinoa NORT , Aix-Marseille Université , INRA, INSERM, 13000 , Marseille , France.
Franck Tourniairea NORT , Aix-Marseille Université , INRA, INSERM, 13000 , Marseille , France.
Julien Astiera NORT , Aix-Marseille Université , INRA, INSERM, 13000 , Marseille , France.
Jianping Yeb Pennington Biomedical Research Center , Louisiana State University System , Baton Rouge , Louisiana 70808 , USA.
Jean-François Landriera NORT , Aix-Marseille Université , INRA, INSERM, 13000 , Marseille , France.
Aix-Marseille Université · FRInserm · FRLouisiana State University System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation of adipose tissue is believed to be a contributing factor to many chronic diseases associated with obesity. Vitamin D (VD) is now known to limit this metabolic inflammation by decreasing inflammatory marker expression and leukocyte infiltration in adipose tissue. In this study, we investigated the impact of VD on microRNA (miR) expression in inflammatory conditions in human and mouse adipocytes, using high-throughput methodology (miRNA PCR arrays). Firstly, we identified three miRs (miR-146a, miR-150, and miR-155) positively regulated by TNFα in human adipocytes. Interestingly, the expression of these miRs was strongly prevented by 1,25(OH)

Indexed as

3T3 CellsAdipocytesAnimalsAnti-Inflammatory AgentsCells, CulturedHumansMaleMiceMice, Inbred C57BLMicroRNAsNF-kappa BTumor Necrosis Factor-alphaVitamin DVitaminsAnti-Inflammatory AgentsMicroRNAsNF-kappa BTumor Necrosis Factor-alphaVitamin DVitaminsadipocyteaP2-p65 transgenic miceInflammationmiRsNF-κBvitamin D

Identifiers

PMID28055298
PMCPMC5873365
OpenAlexW2570767274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.