ArticleBiomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals
Salivary protein changes in response to acute stress in medical residents performing advanced clinical simulations: a pilot proteomics study.
Article in Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- A scoping review of emotions and related constructs in simulation-based education research articles.Advances in simulation (London, England) · 2023Article
- HPLC method with post-column derivatization for the analysis of endogenous histidine in human saliva validated using the total-error concept.Amino acids · 2022Article
- Identification of bone morphogenetic protein 4 in the saliva after the placement of fixed orthodontic appliance.Progress in orthodontics · 2021Observational
- Salivary Proteome Changes in Response to Acute Psychological Stress Due to an Oral Exam Simulation in University Students: Effect of an Olfactory Stimulus.International journal of molecular sciences · 2021Article
- Salivary Biomarkers and Work-Related Stress in Night Shift Workers.International journal of environmental research and public health · 2021Article
- Human body-fluid proteome: quantitative profiling and computational prediction.Briefings in bioinformatics · 2021Review
- Changes in salivary proteome before and after cigarette smoking in smokers compared to sham smoking in nonsmokers: A pilot study.Tobacco induced diseases · 2021Article
- THE ROLE OF NEW TECHNOLOGIES IN DEFINING SALIVARY PROTEIN COMPOSITION FOLLOWING PLACEMENT OF FIXED ORTHODONTIC APPLIANCES - BREAKTHROUGH IN THE DEVELOPMENT OF NOVEL DIAGNOSTIC AND THERAPEUTIC PROCEDURES.Acta clinica Croatica · 2020Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
contextQuantitative changes of salivary proteins due to acute stress were detected.
objectiveTo explore protein markers of stress in saliva of eight medical residents who performed emergency medicine simulations. MATERIALS AND
methodsSaliva was collected before the simulations, after the simulations, and following morning upon waking. Proteins were separated by sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE), identified by mass spectrometry (MS), and relatively quantified by densitometry.
resultsSalivary alpha-amylase and S-type cystatins significantly increased, while the ∼26 kDa and low-molecular weight (MW) (<10 kDa) SDS-PAGE bands exhibited changes after stress. DISCUSSION AND
conclusionAlpha-amylase and cystatins are potential salivary markers of acute stress, but further validation should be performed using larger sample populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.